Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of corn oligopeptide in China. Welcome to wholesale bulk high quality corn oligopeptide for sale here from our factory. Good service and reasonable price are available.
Corn Oligopeptide is a mixture of small molecule peptides composed of 2-10 amino acid residues obtained by shredding large molecule proteins from corn gluten meal/Zein using enzymatic hydrolysis technology. The molecular weight is concentrated in the range of 200-1000 Da, belonging to the family of small molecule active peptides of plant origin, along with soybean oligopeptides and wheat oligopeptides. The appearance is a fine powder ranging from light yellow to brownish yellow, with no lumps, visible impurities, or unpleasant odors. It has a slight odor unique to corn peptides. After dissolving in water, it forms a clear to slightly yellow transparent solution with good fluidity and a solubility of ≥ 98%. Mainly used for lowering blood pressure, antioxidation, and accelerating energy metabolism.
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Corn Oligopeptide COA
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| Certificate of Analysis | ||
| Compound name | Corn Oligopeptide | |
| Grade | Pharmaceutical grade | |
| CAS No. | N/A | |
| Quantity | 50g | |
| Packaging standard | PE bag+Al foil bag | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
| Lot No. | 202601090067 | |
| MFG | Jan 9th 2026 | |
| EXP | Jan 8th 2029 | |
| Item | Enterprise standard | Analysis result |
| Appearance | White or almost white powder | Conformed |
| Water content | ≤5.0% | 0.59% |
| Loss on drying | ≤1.0% | 0.49% |
| Heavy Metals | Pb≤0.5ppm | N.D. |
| As≤0.5ppm | N.D. | |
| Hg≤0.5ppm | N.D. | |
| Cd≤0.5ppm | N.D. | |
| Purity (HPLC) | ≥99.0% | 99.98% |
| Single impurity | <0.8% | 0.69% |
| Total microbial count | ≤750cfu/g | 150 |
| E. Coli | ≤2MPN/g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (by GC) | ≤5000ppm | 500ppm |
| Storage | Store in a sealed, dark, and dry place below -20°C | |
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Corn Oligopeptide Drug for the Feed Farming Industry
Corn Oligopeptide (COP) is a small molecule peptide mixture made from corn protein powder through directed enzymatic hydrolysis, membrane separation, concentration and drying. The peptide chain consists of 2-10 amino acids, with an average molecular weight of 500-1000Da and a protein digestibility of ≥ 90%. It is a new green, efficient and safe feed additive and protein raw material. Its core advantages include high branched chain amino acids (BCAAs), high water solubility, high stability, easy absorption, no anti nutritional factors, and both nutritional and physiological activities. It can be fully adapted to all scenarios of livestock, poultry, aquaculture, and special breeding, achieving seven core values of promoting growth, enhancing immunity, protecting the intestines, resisting stress, improving meat quality, reducing feed efficiency, and reducing antibiotics. This article discusses the basic physicochemical properties and feed compatibility, core mechanisms of action (nutrient absorption/intestinal health/immune antioxidant/metabolic regulation), precision applications in livestock and poultry farming (pigs/chickens/ducks/ruminants), efficient aquaculture solutions (fish/shrimp/crabs/specialties), and expansion of specialty farming (rabbits/pigeons/fur animals)
Basic physicochemical properties of COP and their adaptability to the feed industry

Definition and Preparation Process
Feed grade corn oligopeptides take corn gluten meal (protein content ≥ 60%), a by-product of corn deep processing, as raw material, and use alkaline protease+neutral protease complex enzymolysis technology to cut macromolecular corn gluten (molecular weight ≥ 10000Da) into 2-8 peptides (proportion ≥ 75%). After membrane separation and desalination, activated carbon bleaching, and spray drying, they are made into light yellow powder, which meets the industry standard QB/T 4707-2014. Feed grade core indicators: crude protein ≥ 80%, oligopeptides ≥ 75%, molecular weight<1000Da ≥ 90%, moisture ≤ 8%, ash ≤ 5%, and water solubility ≥ 90%.
amino acid composition
High branched chain amino acids (BCAA, 15% -20%): leucine (12% -15%), isoleucine, valine, promote muscle synthesis, anti fatigue, improve exercise ability, suitable for livestock and poultry weight gain and aquatic muscle development.
High glutamic acid (20% -25%): repairs intestinal mucosa, enhances immunity, promotes digestive enzyme secretion, and is suitable for the vulnerable period of young animal intestines.

High sulfur-containing amino acids (methionine+cysteine, 5% -8%): Corn protein has a natural advantage, promoting feather/hair growth, improving fur luster, enhancing egg quality, and is suitable for poultry and fur animals.
High levels of alanine and proline (10% -15%): promote metabolism, enhance stress resistance, and improve meat flavor.
Low aromatic amino acids (≤ 5%): reduce liver burden, suitable for young/sick animals.
Lutein+zeaxanthin (50-100mg/kg): a natural coloring agent that improves the skin/egg yolk color and aquatic body color of poultry, replacing artificial colors.
Core adaptation advantages of the feed industry
Rapid absorption, low energy consumption: molecular weight<1000Da, absorbed directly into the intestine without digestion, absorption rate ≥ 95%, peak blood concentration reached in 15-30 minutes, can be directly utilized by young animals (piglets/chicks/fish fry), sick animals, and postoperative animals, reducing intestinal burden.
Acid and heat stable, suitable for processing: pH 3.0-8.0 stable, 121 ℃ granulation for 30 minutes, activity retention ≥ 92%, high temperature resistance, granulation resistance, not easily browning, suitable for processing granular materials, puffed materials, and premix materials.

No anti nutritional factors, high safety: The enzymatic hydrolysis process thoroughly degrades anti nutritional factors such as phytic acid, tannins, trypsin inhibitors, etc. in corn protein, without sensitization, toxins, or residues, replacing easily allergenic raw materials such as soybean meal and fish meal, and reducing the risk of allergic diarrhea.
Multi functional, one peptide multi effect: It combines seven activities: nutritional supplementation, intestinal protection, immune enhancement, antioxidant, stress resistance, metabolic regulation, and quality improvement. It can replace antibiotics, growth promoters, intestinal health supplements, and antioxidants, achieving green and antibiotic free farming.
Good water solubility, suitable for multiple dosage forms: water solubility ≥ 90%, can be added to granular materials, powder materials, liquid materials, drinking water, fermentation materials, suitable for various administration methods such as mixing, drinking water, and oral administration.
Widely sourced and cost-effective: using by-products from deep processing of corn as raw materials, the cost is lower than fish meal, whey peptide, and soy peptide, and the protein efficiency ratio (PER) is 30% -50% higher than ordinary corn protein powder, significantly reducing costs and increasing efficiency.

The Core Mechanism of Corn Oligopeptides in Feed Farming
Efficient nutrient absorption: improves protein utilization and promotes growth
Advantages of small peptide transport
There is a small peptide transporter (PEPT1) in the animal intestine that can specifically absorb 2-3 peptides, with an absorption efficiency 2-3 times that of free amino acids and 5-10 times that of intact proteins. The proportion of 2-3 peptides in COP is ≥ 50%, which can directly activate the PEPT1 carrier, quickly enter intestinal mucosal cells, bypass the bottleneck of amino acid competition absorption, and increase protein digestibility from 60% -70% of ordinary corn protein powder to over 90%.
Rapid energy supply and muscle synthesis
Direct oxidation of branched chain amino acids (BCAAs) for energy supply: reduces muscle glycogen consumption, improves energy supply efficiency, shortens growth cycle, and increases daily weight gain.
Leucine activates mTOR pathway: promotes muscle protein synthesis, inhibits muscle breakdown, increases lean meat percentage, and improves meat quality.
Fast supplementation of free amino acids: Enzymatic hydrolysis produces 10% -15% free amino acids, which directly participate in metabolism and promote growth hormone secretion.
Intestinal health protection: repairing mucous membranes, regulating microbiota, preventing diarrhea
Repair intestinal mucosa and enhance barrier function
High glutamine (20% -25%): the preferred energy source for intestinal mucosal cells, promoting intestinal epithelial cell proliferation, repairing damaged mucosa, increasing intestinal villus height, reducing crypt depth, and enhancing intestinal barrier integrity.
Small peptides promote intestinal development: stimulate DNA synthesis in intestinal mucosal cells, promote intestinal maturation, and shorten the weaning stress period in young animals.
Regulating gut microbiota and inhibiting harmful bacteria
Promoting the proliferation of beneficial bacteria: Beneficial bacteria such as Bifidobacterium, Lactobacillus, and Bacillus can rapidly multiply using small peptides, increasing the proportion of beneficial bacteria by 30% -50%.
Inhibition of harmful bacterial adhesion: Small peptides competitively bind to intestinal mucosal harmful bacterial receptors, preventing the adhesion and colonization of Escherichia coli, Salmonella, and Clostridium perfringens, reducing the risk of intestinal infection, and decreasing the incidence of diarrhea.


Enhance digestive enzyme activity and improve digestive function
Stimulate the secretion of digestive enzymes: increase the activity of pepsin, trypsin, amylase, and lipase (by 20% -40%), enhance feed digestion and absorption, and reduce feed efficiency.
Reduce intestinal inflammation: reduce the release of pro-inflammatory factors (TNF - α, IL-6), alleviate intestinal inflammation, reduce mucosal damage, and improve post weaning diarrhea and watery stools in young animals.
Immune enhancement and antioxidant: enhancing disease resistance and reducing mortality rate
Enhance non-specific immunity
Activate immune cells: promote macrophage phagocytic ability (increased by 40% -60%), NK cell activity (increased by 30% -50%), T/B lymphocyte proliferation, and enhance the body's ability to resist infections.
Boosting immunoglobulin: promoting the synthesis of IgG, IgA, and IgM, enhancing humoral immunity, improving mucosal immunity, and reducing respiratory and digestive tract infection rates.

Antioxidant and free radical scavenging
Direct elimination of free radicals: Tyrosine and proline in peptide chains provide hydrogen atoms, neutralize superoxide anions, hydroxyl radicals, and lipid peroxides, and alleviate oxidative stress damage.
Enhance endogenous antioxidant enzymes: increase SOD, GSH-PX, CAT activity (by 20% -40%), reduce serum MDA (malondialdehyde) content (by 30% -50%), protect cells, delay aging, and enhance stress resistance.
Stress resistance: Relieve weaning/weaning/transportation/heat stress
Regulating neuroendocrine function and relieving stress
Promote the production of gamma aminobutyric acid (GABA): inhibit central nervous system excitation, calm the mind, relieve anxiety, and reduce the secretion of stress hormones (cortisol, adrenaline).
Regulating 5-hydroxytryptamine and dopamine: Relieve tense emotions, reduce stress reactions, and lower mortality, weight loss, and yield reduction caused by transportation, social distancing, and heat stress.


Improve metabolism during stress period and reduce losses
Enhance energy reserves: Increase liver glycogen and muscle glycogen reserves (by 30% -50%), provide rapid energy supply during stress periods, and reduce weight loss.
Protecting the intestinal barrier: During the stress period, the intestinal mucosa is easily damaged. Corn oligopeptide can quickly repair the mucosa, maintain intestinal function, and reduce stress-induced diarrhea and dehydration.
Metabolic regulation: protecting the liver and kidneys, improving fat metabolism, and lowering blood lipids
Protect the liver and kidneys, reduce metabolic burden
High F-value (branched/aromatic amino acid ratio ≥ 3): reduces blood ammonia, alleviates liver detoxification burden, prevents fatty liver, improves liver function, and enhances liver metabolic efficiency.


Promote alcohol/toxin metabolism: activate liver alcohol dehydrogenase and aldehyde dehydrogenase, accelerate the metabolism of mycotoxins and drug residues in feed, and reduce liver and kidney damage.
Regulating fat metabolism and improving meat quality
Inhibit fat synthesis: reduce the activity of fatty acid synthase, decrease fat deposition, increase lean meat percentage, and lower abdominal fat percentage.
Promote fat breakdown: activate lipase, accelerate fat mobilization, improve meat flavor, and reduce greasiness
reference
- Beijing Boyan Zhishang Information Consulting Co., Ltd Report on the Development Status and Market of China's COPs Industry in 2026.
- College of Fisheries, East China Normal University. Research on the Application Mechanism of Enzymatic Hydrolyzed Corn Protein Powder in Aquaculture.2025.
- Chinese Society of Animal Husbandry and Veterinary Medicine. Expert consensus on the application of peptide additives in livestock and poultry breeding.2024.
- The Protective Effects of COPs on Acute Alcoholic Liver Disease by Inhibiting the Activation of Kupffer Cells NF-κB/AMPK Signal Pathway(https://pmc.ncbi.nlm.nih.gov/articles/PMC9572984/)
- Corn oligopeptide protect against early alcoholic liver injury in rats(https://www.sciencedirect.com/science/article/abs/pii/S0278691512002761)
FAQ
What is COP?
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Corn oligopeptides (COPs) are protein hydrolysates produced by enzymatic treatments, which have shown potential bioactivities, such as inhibiting angiotensin I-converting enzyme, resisting lipid peroxidation and anti-oxidant.
What is oligopeptide good for?
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Oligopeptides interfere with the regulation of collagen and elastin production which accounts for many of the changes in ageing skin such as skin laxity, loss of skin plumpness and enlarged pores. Finally, it also helps to regulate pigment (melanin synthesis) which can help to treat pigmentary disorders.
Is corn high in carotenoids?
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Corn contains significant amounts of lutein, zeaxanthin, and other carotenoids and is a popular vegetable in the American diet. Corn is readily available as fresh, canned or frozen.
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