Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of whey protein peptide in China. Welcome to wholesale bulk high quality whey protein peptide for sale here from our factory. Good service and reasonable price are available.
Whey protein peptide is a mixture of small-molecule bioactive peptides produced from bovine whey protein via targeted enzymatic hydrolysis, separation and purification. It is mainly degraded from whey proteins including β-lactoglobulin, α-lactalbumin and lactoferrin. As a natural functional ingredient with high nutritional value and multiple biological activities, it is widely recognized. A high-quality milk-derived bioactive peptide, the product is rich in essential amino acids and branched-chain amino acids required by the human body.
It can not only supplement nutrients for the human body but also regulate a variety of physiological functions. It has broad applications in functional foods, sports nutrition, maternal and infant foods as well as biomedicine, and is currently one of the research hotspots in food science and nutrition.
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Whey Protein Peptide COA
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| Certificate of Analysis | ||
| Compound name | Whey Protein Peptide | |
| Grade | Pharmaceutical grade | |
| CAS No. | 84082-51-9 | |
| Quantity | 37g | |
| Packaging standard | PE bag+Al foil bag | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
| Lot No. | 202601090056 | |
| MFG | Jan 9th 2026 | |
| EXP | Jan 8th 2029 | |
| Structure | N\A | |
| Item | Enterprise standard | Analysis result |
| Appearance | White or almost white powder | Conformed |
| Water content | ≤5.0% | 0.35% |
| Loss on drying | ≤1.0% | 0.78% |
| Heavy Metals | Pb≤0.5ppm | N.D. |
| As≤0.5ppm | N.D. | |
| Hg≤0.5ppm | N.D. | |
| Cd≤0.5ppm | N.D. | |
| Purity (HPLC) | ≥99.0% | 99.78% |
| Single impurity | <0.8% | 0.24% |
| Total microbial count | ≤750cfu/g | 200 |
| E. Coli | ≤2MPN/g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (by GC) | ≤5000ppm | 621ppm |
| Storage | Store in a sealed, dark, and dry place below 2-8°C | |
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2.1 Antioxidant and Anti-inflammatory Effects
Whey protein peptide is a natural and highly effective antioxidant. It eliminates free radicals, relieves oxidative stress damage, delays cellular senescence and reduces the risk of chronic diseases through multiple pathways. Its peptide chains contain active amino acid residues such as tyrosine, tryptophan and cysteine, which directly scavenge reactive oxygen species including superoxide anions and hydroxyl radicals, block free radical chain reactions, and mitigate damage to cell membranes and organelles caused by lipid peroxidation.
Meanwhile, it upregulates the activities of endogenous antioxidant enzymes such as superoxide dismutase and glutathione peroxidase, enhancing the function of the body's intrinsic antioxidant system and improving antioxidant capacity fundamentally.In terms of anti-inflammation, it inhibits the excessive release of pro-inflammatory factors including tumor necrosis factor-α and interleukin-6, alleviating low-grade inflammation and subsequent tissue damage. Relevant studies have proven that long-term supplementation with it effectively relieves oxidative stress and inflammation induced by metabolic disorders. It exerts favorable repairing and protective effects against skin aging as well as hepatic and renal oxidative damage, without the potential toxic side effects of synthetic antioxidants.

2.2 Immunomodulatory and Anti-allergic Effects
It possesses excellent immunomodulatory activity. It bidirectionally regulates immune function to strengthen bodily resistance and lower the sensitization risk of milk protein.
For immune enhancement, it stimulates the proliferation and activation of immune cells such as macrophages, natural killer (NK) cells and lymphocytes, improves their phagocytic capacity and immune response efficiency, promotes the synthesis of immunoglobulins, and boosts the body's defense against bacterial and viral invasion. Long-term supplementation effectively improves physical fitness and reduces the incidence of respiratory and intestinal infections among people with low immunity.
In terms of anti-allergy, enzymatic hydrolysis destroys the allergenic epitopes of large-molecule whey protein, and the resulting small-molecule peptide fragments show no allergenicity, markedly reducing the occurrence of milk protein allergy. In addition, it regulates the Th1/Th2 immune balance, inhibits the release of allergic mediators and relieves symptoms of allergic rhinitis and dermatitis. It meets the nutritional supplementation demands of infants and people with allergic constitutions, and has been widely applied in the development of hypoallergenic infant formula foods.

2.3 Blood Pressure Regulation and Cardiovascular Protection
It is a typical angiotensin-converting enzyme (ACE) inhibitory peptide with safe and mild hypotensive effects, capable of regulating blood pressure and protecting cardiovascular health effectively. Its core mechanism is to inhibit ACE activity, block the conversion of angiotensin I to vasoconstrictive angiotensin II, reduce vasoconstriction and dilate peripheral blood vessels, thereby steadily lowering blood pressure. It will not cause adverse reactions such as abrupt blood pressure drop or dizziness, making it suitable for patients with mild essential hypertension and sub-health populations with elevated blood pressure.
Furthermore, whey protein peptide modulates lipid metabolism, reduces serum levels of total cholesterol, triglycerides and low-density lipoprotein, and increases high-density lipoprotein. It inhibits lipid deposition on blood vessel walls to prevent atherosclerosis. It also exhibits antithrombotic activity, suppressing abnormal platelet aggregation, lowering blood viscosity and improving blood circulation. It comprehensively maintains cardiovascular homeostasis, and long-term intake can effectively reduce the risk of chronic cardiovascular diseases.
2.4 Muscle Anabolism Promotion and Post-exercise Recovery
Rich in branched-chain amino acids including leucine, it is a premium nutritional ingredient for muscle repair and growth among athletes and fitness enthusiasts, and is extensively used in the field of sports nutrition.
Compared with conventional whey protein, these small-molecule peptides can be rapidly absorbed by the intestinal tract and enter the bloodstream in a short time.They provide sufficient amino acid substrates for skeletal muscle synthesis, effectively promote muscle protein anabolism after exercise, inhibit muscle protein breakdown, and increase muscle mass and strength.
For physical fatigue and muscle soreness caused by high-intensity exercise, it quickly replenishes consumed nutrients, removes metabolic wastes such as lactic acid, alleviates exercise-induced fatigue and shortens the recovery period. Additionally, it optimizes nitrogen balance and reduces muscle loss during exercise. It serves as daily nutrition for fitness enthusiasts and professional athletes, and also helps the elderly slow down muscle loss, prevent sarcopenia and improve physical performance.

3.1 Raw Material Pretreatment
Industrial production of whey protein peptide mainly adopts whey protein powder and whey concentrate as raw materials. Pretreatment is a fundamental procedure to guarantee the quality and activity of peptide fragments.
First, dissolve and prepare the raw materials: mix whey protein raw materials with deionized water at a fixed ratio and stir thoroughly to prepare a protein solution with a mass fraction of 5%–10%. An excessively high concentration will lead to incomplete enzymatic hydrolysis, while an overly low concentration will reduce production efficiency.
Subsequently, perform pasteurization via water bath heating at 85–90 °C for 10–15 minutes. This process kills microorganisms in raw materials, moderately denatures the spatial structure of whey protein, unfolds peptide chains and exposes enzymatic hydrolysis sites to create optimal conditions for subsequent reactions.
After sterilization, cool the solution rapidly to the suitable temperature for enzymatic hydrolysis and remove insoluble impurities to ensure a pure and homogeneous raw material system.
3.2 Targeted Enzymatic Hydrolysis
Enzymatic hydrolysis is the mainstream technology for producing this bioactive peptide at present, featuring mild reaction conditions, complete retention of peptide activity and no harmful by-products. Compound proteases are commonly used in industrial production, including papain, pepsin and alkaline protease. Suitable enzymes can be selected according to the target peptide activity.
Adjust the pH value and temperature of the pretreated protein solution to match the optimal reaction conditions of the selected protease. Generally, alkaline protease reacts at 50–55 °C with a pH of 8.0–8.5, while papain works at 45–50 °C with a pH of 6.0–7.0.
Add protease at a dosage of 2%–5% based on the substrate mass, and conduct constant-temperature stirring hydrolysis for 3–5 hours. The degree of protein hydrolysis is precisely controlled by adjusting hydrolysis duration and enzyme dosage to avoid excessive hydrolysis that produces free amino acids, so as to retain the content and biological activity of small-molecule active peptides.
3.3 Enzyme Deactivation, Separation and Purification
Upon completion of enzymatic hydrolysis, perform high-temperature enzyme deactivation immediately. Heat the solution to 90–95 °C and maintain the temperature for 5–8 minutes to thoroughly inactivate proteases and terminate the hydrolysis reaction, preventing further degradation of peptide fragments.
Cool the solution to room temperature after deactivation, and remove enzyme residues and unhydrolyzed macromolecular protein impurities by centrifugation to obtain crude peptide liquid. Ultrafiltration is then applied for fractional purification: use an ultrafiltration membrane with a molecular weight cutoff of 1000 Da to remove macromolecular proteins and impurities and enrich small-molecule active peptides.
Finally, vacuum concentration and spray drying are adopted to remove moisture and obtain powdered finished this bioactive peptide. This process maximally preserves the biological activity of peptides and improves product purity and stability.
References
- Bo Z H, Wei J Z, Su Q, et al. Research progress on preparation and biological activities of milk protein peptides[J]. Journal of Dairy Science and Technology, 2025, 48(4): 1-8.
- Lou X X, Ma H P, Gao J J, et al. Advances in research on biological functions of milk-derived bioactive peptides[J]. Journal of Dairy Science and Technology, 2024, 47(3): 6-12.
- Whey protein regulation of muscle protein synthesis: From molecular mechanisms to physiological effects.(https://www.sciencedirect.com/science/article/abs/pii/S2212429226007777)
- Whey isolate vs. concentrate: what's the difference?(https://www.hollandandbarrett.com/the-health-hub/sports-nutrition/protein/whey-protein/whey-isolate-vs-concentrate/)
FAQ
What does whey peptide do?
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These isolated whey peptides provide the following benefits: increased release of insulinlike growth factor, improved overall endocrine hormone response, increased nitrogen utilization and retention, increased intracellular glutathione and anti–aging antioxidants, improved immune function ...
Does whey protein lower cortisol?
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Yes, whey protein can help lower or stabilize cortisol levels. It is particularly effective at blunting the cortisol spikes that occur after strenuous exercise or during periods of acute stress.
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