Sodium Cholate CAS 361-09-1
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Sodium Cholate CAS 361-09-1

Sodium Cholate CAS 361-09-1

Product Code: BM-1-2-221
CAS number: 361-09-1
Molecular formula: C24H41NaO5
Molecular weight: 432.58
EINECS number: 206-643-5
MDL No.: MFCD00064138
Hs code: 29173990
Analysis items: HPLC>99.0%, LC-MS
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Manufacturer: BLOOM TECH Changzhou Factory
Technology service: R&D Dept.-4

 

Sodium cholate, molecular formula C24H41NaO5, CAS 361-09-1, It is a general term for a type of bile acid present in bile, usually in the form of light yellow or brownish yellow powder. The powder is odorless or has a fresh bile odor, with a sweet taste at first and a bitter taste later. Its alkali metal salts are easily soluble in water and alcohol. Natural bile acids can form bile acid salts that bind with glycine or taurine and with sodium and cadmium ions, and exist in dry bile. It is a product of the binding of bile acids and sodium ions. It is an anionic, non denaturing detergent and surfactant commonly used in protein research for the extraction of membrane receptors and other membrane proteins, promoting membrane protein dissolution and maintaining its natural state. It is also commonly used in liposome preparation, lipid compound separation, cell lysis, and affinity chromatography to prevent non-specific binding. It is still a cell culture medium additive.

Produnct Introduction

Chemical Formula

C24H39NaO5

Exact Mass

430.27

Molecular Weight

430.56

m/z

430.27 (100.0%), 431.27 (26.0%), 432.28 (2.7%), 432.27 (1.0%)

Elemental Analysis

C, 66.95; H, 9.13; Na, 5.34; O, 18.58

Sodium Cholate | Shaanxi BLOOM Tech Co., Ltd

CAS 361-09-1 Sodium Cholate structure | Shaanxi BLOOM Tech Co., Ltd

Applications | Shaanxi BLOOM Tech Co., Ltd

Sodium cholate, as a chemical substance extracted from cow bile or other animal bile, has multiple uses and a wide range of application examples.

Medical field

Sodium Cholate drug | Shaanxi BLOOM Tech Co., Ltd

1. Choleretic drugs

 

It is one of the important components of bile and has the function of promoting bile secretion and excretion, so it is widely used in the treatment of diseases such as bile deficiency and cholecystitis. By taking sodium cholte, the flow of bile can be increased, which helps to eliminate stagnant bile and foreign objects in the biliary tract, thereby alleviating symptoms of biliary diseases.

Application example:

 

Cholecystitis treatment: Sodium cholte tablets are a commonly used medication for treating cholecystitis. By taking sodium cholte tablets, the secretion and excretion of bile can be promoted, reducing the pain and discomfort caused by cholecystitis.
Bile deficiency: For patients with insufficient bile secretion, sodium cholte can be used as a supplementary treatment to help improve the secretion and excretion function of bile.

Sodium Cholate cholecystitis | Shaanxi BLOOM Tech Co., Ltd
Sodium Cholate regulate | Shaanxi BLOOM Tech Co., Ltd

2. Regulate cholesterol metabolism

 

Participate in the metabolic process of cholesterol, promote synthesis and excretion in the liver, and help maintain cholesterol balance. It can lower the saturation of cholesterol in bile, reduce the formation of cholesterol crystals, and thus prevent the occurrence of gallstones.

Application example:

 

Gallstone prevention: By taking it, the concentration of cholesterol in bile can be reduced, and the formation of cholesterol crystals can be reduced, thereby preventing the occurrence of gallstones.
Lowering blood lipids: It can also be used as an adjuvant therapy for lipid-lowering drugs, helping to lower cholesterol and triglyceride levels in the blood.

Sodium Cholate cholesterol | Shaanxi BLOOM Tech Co., Ltd
Sodium Cholate emulsifying | Shaanxi BLOOM Tech Co., Ltd

3. Improve digestive function

 

It has an emulsifying effect, which can emulsify fat into droplets, increase the action area of pancreatic lipase, and promote the digestion and absorption of fat. Meanwhile, it can also promote lipid metabolism, including the synthesis and transport of cholesterol, triglycerides, and lipoproteins.

Application example:

 

Digestive disorders: For patients with digestive disorders, especially those with fat dyspepsia, it can be used as an adjuvant therapy to help improve the digestion and absorption function of fat.
Promoting nutrient absorption: It can also be used as a nutritional supplement to help improve the absorption and utilization of nutrients, especially for patients who require a high protein, high-fat diet.

Sodium Cholate uses | Shaanxi BLOOM Tech Co., Ltd
Sodium Cholate effect | Shaanxi BLOOM Tech Co., Ltd

4. Anti inflammatory effect

 

It has a certain anti-inflammatory effect and can be used to treat certain inflammatory diseases, such as dermatitis, arthritis, etc. Its anti-inflammatory mechanism may be related to reducing inflammatory response and decreasing the release of inflammatory mediators.

Application example:

 

Skin inflammation treatment: can be used as an external medication to treat inflammatory skin diseases such as dermatitis. Local application can alleviate symptoms such as redness, swelling, and itching caused by skin inflammation.
Arthritis treatment: It can also be used as an adjuvant therapy for arthritis by reducing inflammation and pain in the joints, improving the symptoms and quality of life of arthritis patients.

Sodium Cholate external | Shaanxi BLOOM Tech Co., Ltd

Food industry

Sodium Cholate food | Shaanxi BLOOM Tech Co., Ltd

1. Food additives

 

It can be used as a food additive, mainly to improve the taste and stability of food. It can be used as an emulsifier, stabilizer, thickener, etc. for the processing and production of various foods.

Application example:

 

Dairy products: In dairy products, it can be used as an emulsifier to help improve the taste and stability of dairy products. For example, adding sodium cholate to yogurt can make it more delicate and have a better taste.
Baked goods: In baked goods, it can be used as a stabilizer and thickener to help improve the taste and texture of baked goods. For example, adding sodium cholat to bread can make it softer and have a better texture.
Meat products: In meat products, it can be used as an emulsifier to help improve the taste and stability of meat products. For example, adding sodium cholat to sausages can make them more delicate, taste better, and help extend their shelf life.

Sodium Cholate dairy | Shaanxi BLOOM Tech Co., Ltd
Sodium Cholate feed | Shaanxi BLOOM Tech Co., Ltd

2. Feed additives

 

It can also be used as a feed additive, mainly to improve the digestive function and nutrient absorption ability of animals. It can be used as an emulsifier, stabilizer, etc. for the processing and production of various types of feed.

Application example:

 

Pig feed: Adding it to pig feed can improve the digestive function and nutrient absorption ability of pigs, thereby enhancing their growth rate and meat quality.
Chicken feed: Adding it to chicken feed can improve the digestive function of chickens, increase their growth rate and egg production rate.
Aquatic feed: Adding it to aquatic feed can improve the digestive function and nutrient absorption capacity of aquatic products, thereby enhancing their growth rate and quality.

Sodium Cholate pig | Shaanxi BLOOM Tech Co., Ltd

Cosmetics industry

Sodium Cholate cosmetics | Shaanxi BLOOM Tech Co., Ltd

1. Emulsifier

 

In the cosmetics industry, it can be used as an emulsifier to help mix oil and water together to form a stable emulsion. The emulsion can be used to make various cosmetics, such as face cream, lotion, shampoo, etc.

Application example:
Face cream: adding face cream as an emulsifier can help to mix oil and water together to form a stable emulsion, thus improving the stability and use effect of face cream.
Shampoo: Adding emulsifiers to shampoo can help disperse the oil and water in the shampoo into tiny particles, thereby improving the cleaning ability and dandruff removal effect of the shampoo.

2. Moisturizing agents

 

It also has a certain moisturizing effect, which can help the skin maintain moisture and moisturization. Therefore, adding sodium cholate to cosmetics can improve the moisturizing effect of the product, making the skin softer, smoother, and more elastic.

Application example:
Moisturizing cream: Adding moisturizing agents to moisturizers can help the skin maintain moisture and hydration, thereby improving the effectiveness of moisturizer use.
Body lotion: add body lotion as a moisturizer to help skin maintain moisture and moisture, thus improving the dryness and roughness of skin.

Sodium Cholate uses | Shaanxi BLOOM Tech Co., Ltd

Other fields

Sodium Cholate research | Shaanxi BLOOM Tech Co., Ltd

1. Biological science research

 

It has a wide range of applications in biological science research. It can be used as an anionic protein detergent for biochemical experiments such as extracting membrane proteins. At the same time, it can also be used as an additive in bacterial culture media, providing necessary nutrition and growth environment for the growth of microorganisms.

Application example:

 

Membrane protein extraction: In biological research, membrane protein extraction is an important experimental step. It can be used as an anionic protein detergent to help separate membrane proteins from cell membranes for subsequent biochemical analysis and research.
Bacterial culture medium additives: Adding an appropriate amount during bacterial culture can provide necessary nutrition and growth environment, promoting bacterial growth and reproduction. This is of great significance for fields such as bacteriology research and drug screening.

Sodium Cholate application | Shaanxi BLOOM Tech Co., Ltd
Sodium Cholate agriculture | Shaanxi BLOOM Tech Co., Ltd

2. In the field of agriculture

 

It also has certain applications in the field of agriculture. It can be used as a synergist for pesticides to enhance their insecticidal and control effects. At the same time, it can also be used as a plant growth regulator to promote plant growth and development.

Application example:

 

Pesticide synergist: Adding an appropriate amount of sodium cholat to pesticides can improve their insecticidal and control effects. This is because it can increase the adhesion and permeability of pesticides on plant surfaces, making them easier for plants to absorb and utilize.
Plant growth regulators: Adding an appropriate amount during plant growth can promote plant growth and development. This is because it can stimulate the division and elongation of plant cells, increasing the growth rate and biomass of plants.

Sodium Cholate suppliers | Shaanxi BLOOM Tech Co., Ltd
Sodium Cholate buy | Shaanxi BLOOM Tech Co., Ltd

3. Industrial applications

 

It also has a wide range of applications in the industrial field. It can be used as a surfactant for the processing and production of various industrial products. At the same time, it can also be used as a cleaning agent, rust inhibitor, etc., to help clean and protect various equipment and materials.

Application example:

 

Surfactant: In industrial products, it can be used as a surfactant to help improve product performance and stability. For example, adding detergent can improve its cleaning ability and stain removal effect.
Cleaning agent: During the cleaning process, it can be used as a cleaning agent to help remove various dirt and grease. For example, adding it during metal cleaning can help remove oil stains and rust from the metal surface.
Rust inhibitor: During the rust prevention process, it can be used as a rust inhibitor to help protect various equipment and materials from corrosion and oxidation. For example, applying on metal surfaces can prevent rusting and corrosion of the metal.

Sodium Cholate uses | Shaanxi BLOOM Tech Co., Ltd

In summary, sodium cholate has a wide range of application fields and multiple uses. In the field of medicine, it can be used as a choleretic drug, regulate cholesterol metabolism, improve digestive function, and have anti-inflammatory effects; In the food industry, it can be used as a food additive and feed additive; In the cosmetics industry, it can be used as an emulsifier and moisturizer; It has also been widely applied in other fields such as biological science research, agriculture, and industrial applications.

faq
 

What is sodium cholate used for?

Sodium cholate is used in the preparation and formulation of certain microbiological diagnostic media. It is used as a manufacturing aid for the extraction and purification of proteins. It is also used as an excipient in certain drug formulations to improve drug bioavailability.

Is sodium cholate a detergent?

Description. Sodium cholate is an anionic detergent with 14 mM CMC. Since three hydroxy groups are located on a steroid ring and one carboxylic group is at the terminus of the molecular structure, there are no definitive lipophilic or hydrophilic regions in the molecule.

What is the purpose of Sodium Deoxycholate?

In pharmaceutical formulations, sodium deoxycholate acts as a solubilizing agent, improving the bioavailability of certain drugs.

Is sodium cholate a bile salt?

Sodium cholate is a bile acid salt, which is applied as a biological detergent. The mixed systems of phospholipid/sodium cholate are used to study the self-assembly of micelles and formation of micellar systems.

Is sodium chlorate harmful to humans?

In the past, the main use of sodium chlorate was as a pesticide, largely to kill weeds and undesirable foliage. Sodium chlorate is harmful to both humans and the environment. Therefore, the sale and use of sodium chlorate in plant protection products and pesticides in the EU is banned.

Is sodium chloride the same as salt?

Is sodium chloride the same as salt?

 

 

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