Sodium thioglycolate, CAS 367-51-1,EINECS 206-696-4, Its molecular formula is C2H3NaO2S and its molecular weight is 114.099. Usually white crystals or white powder, with deliquescence, which means it is easy to absorb moisture from the air. When it is first made, it may have a slight special odor. Exposure to air or contact with iron can cause discoloration. If the color turns yellow or black, it indicates that it has deteriorated and cannot be used again. It is easily soluble in water and slightly soluble in ethanol. This solubility enables it to form a higher concentration solution in aqueous solutions, making it easier to apply in fields such as biochemical research and chemical hot melt preparation. Meanwhile, due to its slight solubility in ethanol, sodium thioglycolte can also exist at lower concentrations in ethanol solutions, providing possibilities for certain specific applications. The pH value is usually around 6.7 (100g/l, H2O, 20 ℃). This pH value makes it weakly acidic or neutral in solution, which is beneficial for its application in certain biochemical reactions and chemical synthesis. In biochemical research, it can be used to maintain reducing conditions in the environment, keeping thiol groups in a reduced state, thereby protecting proteins from inactivation. This property makes sodium thioglycolte one of the commonly used reducing agents in biochemical experiments. In addition, it can also be used for the preparation of chemical cold perm solutions, and by adjusting its concentration and pH value, the curl of hair can be controlled.
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Chemical Formula |
C2H3NaO2S |
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Exact Mass |
113.98 |
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Molecular Weight |
114.09 |
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m/z |
113.98 (100.0%), 115.97 (4.5%), 114.98 (2.2%) |
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Elemental Analysis |
C, 21.05; H, 2.65; Na, 20.15; O, 28.05; S, 28.10 |
Sodium Thioglycolate, also known as sodium mercaptoacetate, is an important chemical substance with a wide range of uses.
Mining sector
The main use in the mining industry is as an inhibitor for copper molybdenum ore flotation. In the flotation process of copper molybdenum ore, the flotation behavior of copper minerals and pyrite can be effectively suppressed, thereby improving the grade of molybdenum concentrate. This application not only improves the utilization rate of minerals, but also reduces environmental pollution and energy consumption.
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In the field of chemical analysis
In the field of chemical analysis, it is commonly used as an analytical reagent to assist scientists in conducting precise chemical analysis. Its unique chemical properties make it an important participant or indicator in certain chemical reactions, enabling accurate determination or analysis of the content or properties of target substances.
Hairdressing industry
It is also used in the preparation of chemical cold perm solutions, providing important raw materials for the hairdressing industry. During the cold perm process, it can change the internal structure of hair, allowing it to bend or curl, thus achieving a hairdressing effect. This application not only satisfies people's pursuit of beauty, but also promotes the development and innovation of the hairdressing industry.
Biological field
In the field of biology, it is used as one of the components of bacterial culture medium. Bacterial culture medium is a mixture of nutrients required for microbial growth and reproduction, and as one of its components, it can provide necessary carbon, nitrogen, or other nutrients for microorganisms to support their growth and reproduction. This application not only contributes to the research and experimentation of microbiology, but also provides a foundation for the application of biotechnology such as biological fermentation and biotransformation.
Iron test reagent
It can also be used as a reagent for iron testing, helping to detect and analyze the content of iron elements. In iron testing, specific chemical reactions can occur with iron ions to produce products with specific colors or properties. By observing and analyzing the color, morphology, or quantity characteristics of these products, the content or existence state of iron elements in the sample can be accurately determined. This application not only contributes to the analysis of iron elements in geological exploration, environmental monitoring, and other fields, but also provides technical support for the recovery and utilization of iron elements in industries such as metallurgy and chemical engineering.
Cosmetics industry
It also plays an important role in the cosmetics industry. Due to its unique chemical properties, it is often used as the main ingredient in hair removal or curling agents. In hair removal agents, they can destroy the structure of hair, making it fragile and easy to shed, thus achieving the effect of hair removal. In curling agents, it can change the internal structure of hair, allowing it to bend or curl and have a certain degree of durability. These applications not only meet people's needs for beauty and fashion, but also drive the development and innovation of the cosmetics industry.
Other applications
In addition to the aforementioned fields, it also has various other applications. For example, in the electroplating industry, it can be used as one of the additives in the plating solution to improve the performance and appearance of the coating. In the textile industry, it can be used as an auxiliary and finishing agent for dyes to improve the dyeing effect and fabric performance. In addition, sodium thioglycolate can also be used to prepare other chemicals or as a catalyst for certain chemical reactions.
Sodium thioglycolte, as an environmentally friendly and pollution-free product, has played a positive role in the application of mining industry. Compared with traditional highly toxic inhibitors, it not only has better inhibitory effects, but also reduces environmental pollution and energy consumption. Meanwhile, attention should also be paid to its safety during use. Due to its potential corrosive, irritating, and toxic properties, strict adherence to relevant safety operating procedures and protective measures is required during storage, transportation, and use. For example, it is necessary to store in a cool and dry place, avoiding direct sunlight and high temperature environments; During transportation, attention should be paid to preventing leaks and collisions; When using, it is necessary to wear protective equipment and avoid direct contact and accidental ingestion.
The toxicity of sodium thioglycolate is a relatively complex issue as it may be influenced by multiple factors, including exposure mode, dosage, duration, and individual differences. The following is a detailed analysis of the toxicity of sodium thioglycolate:
Acute toxicity:
Sodium thioglycolate may have toxic effects on the human body under acute exposure. This mainly depends on the dosage and method of exposure. For example, if sodium thioglycolate is ingested by mistake, it may cause serious toxic reactions. This toxic reaction may include symptoms such as nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, etc. In severe cases, it may even lead to life-threatening situations. Therefore, when handling and using sodium thioglycolate, it is necessary to strictly follow safety operating procedures to prevent ingestion and skin contact.
Skin irritation and corrosiveness:
Sodium thioglycolate may cause irritation and corrosiveness to the skin. After skin contact, symptoms such as redness, swelling, pain, and itching may occur. Long term or high concentration skin contact may lead to skin ulcers or necrosis. Therefore, appropriate protective equipment such as gloves, masks, and goggles must be worn when handling and using sodium thioglycolate to prevent skin contact.
Eye irritation:
Sodium thioglycolate may also cause eye irritation. If the eyes come into contact with sodium thioglycolate, symptoms such as pain, tears, and redness may occur. In severe cases, it may even lead to visual impairment. Therefore, special care must be taken when handling and using sodium thioglycolate to avoid eye contact. If it accidentally comes into contact with the eyes, rinse immediately with plenty of water and seek medical attention as soon as possible.
Allergenicity:
Sodium thioglycolate may be allergenic, meaning it may cause allergic reactions. The symptoms of allergic reactions may include rash, itching, difficulty breathing, laryngeal edema, etc. For people who are sensitive to sodium thioglycolate, even small amounts of exposure may cause serious allergic reactions. Therefore, it is best to conduct an allergy test before using sodium thioglycolate to ensure safety.
Other potential hazards:
In addition to the toxic effects mentioned above, sodium thioglycolate may also pose potential hazards to the environment and ecosystems. For example, it may contaminate water sources and soil, causing toxic effects on aquatic and terrestrial organisms. Therefore, when handling and using sodium thioglycolate, it is necessary to strictly comply with environmental regulations to ensure proper disposal of waste.
Suggestions for safe use:
When using sodium thioglycolate, safety operating procedures and protective measures must be strictly followed.
Avoid direct contact with skin, eyes, and mouth.
Wear appropriate protective equipment such as gloves, masks, and goggles during use.
Avoid inhaling sodium thioglycolate in the form of dust or gas.
If accidentally in contact with sodium thioglycolate, rinse immediately with plenty of water and seek medical attention as soon as possible.
Pay attention to fire and explosion prevention measures during handling and use.
Abandoned sodium thioglycolate should be properly disposed of in accordance with relevant environmental regulations.
In summary, sodium thioglycolate has certain toxic effects, including acute toxicity, skin irritation and corrosiveness, eye irritation, sensitization, and other potential hazards. Therefore, when using sodium thioglycolate, it is necessary to strictly follow safety operating procedures and protective measures to ensure the safety of personnel and the environment.
faq
What is sodium thioglycolate used for?
Sodium thioglycolate is used primarily in the cosmetic industry as an antioxidant, depilating agent, hair waving/straightening agent, and reducing agent. Sodium thioglycolate's primary cosmetic use is in depilatories.
What does sodium thioglycolate do?
Sodium thioglycolate is commonly used in microbiology as a reducing agent in microbial culture media to facilitate the growth of anaerobic organisms. It helps to maintain anaerobic conditions by reducing oxygen and creating an environment suitable for the growth of microbes that require low oxygen levels.
Is thioglycolic acid safe for hair?
While depilatory creams and perm solutions containing diluted thioglycolic acid are generally considered safe when used as directed, prolonged or excessive exposure may lead to adverse effects.
What is the function of sodium thioglycolate in the FTM?
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