Sodium diethyldithiocarbamate, chemical formula (C2H5) 2ncssna, white to colorless flake crystal. Hygroscopic. It is easily soluble in water, ethanol, methanol and acetone, but insoluble in ether and benzene. It can be used as copper reagent in experiments.
There are three chemical properties:
1、Oxidized to disulfide
The oxidation of sodium diethyldithiocarbamate produces disulfide, namely, colchicine disulfide :
2 NaS2CNEt2 + I2 → Et2NC ( S ) S-SC ( S ) NEt2 + 2NaI
This disulfide was sold as an anti-alcoholic drug under the names of Antabuse and Disulfiram. The chlorination of the disulfide can provide aminothiocarbonyl chloride.
2、As a ligand
Diethyldithiocarbamate can chelate with many ' soft ' metal ions through two sulfur atoms. Other more complex bonding modes are also known, such as using one of two sulfur atoms as a single-tooth ligand or bridging ligand. Because it can form a planar square complex with copper ions and the gray-green complex can be extracted by carbon tetrachloride, it is sometimes called/3、copper reagent.
Spin trapping of nitric oxide free radicals
Diethyldithiocarbamate-iron complex is one of the few methods that can provide research on the formation of nitric oxide ( NO ) free radicals in biological materials. Although the tissue half-life of NO is so short that it cannot be detected, NO is easy to combine with this complex. The formed mononitroso-iron complex ( E : MNIC ) is stable and can be detected in the spectrum by electron spin resonance ( EPR ).
Sodium diethyldithiocarbamate can be obtained by mixing carbon disulfide and diethylamine and neutralization with sodium hydroxide :
CS2 + HN ( C2H5 ) 2 + NaOH → NaS2CN ( C2H5 ) 2 + H2O
Other dithiocarbamates can also be obtained by mixing secondary amine and carbon disulfide in the same way. They are usually used as chelating ligands of transition metal ions and precursors of components in herbicides and sulfides.