3-Hydroxytyramine hydrochloride, also known as dopamine hydrochloride, is an organic compound that appears as white needle shaped crystals or crystalline powder, or as gray white crystals. It is easily soluble in water, soluble in methanol and hot 95% ethanol, soluble in sodium hydroxide solution, and insoluble in ether, chloroform, and benzene. It is a vasopressor and a dopamine D1-5 receptor agonist, widely present in various animals as a catecholamine neurotransmitter. It can excite the heart, increase renal blood flow, and is clinically used to treat hemorrhagic, cardiogenic, and septic shock. Dopamine hydrochloride is also used as a biochemical reagent in scientific research and experiments. It can be prepared through the ring opening reaction of piperonylamine. The specific steps include adding pepper ethylamine and phenol to the reaction vessel, cooling and slowly adding hydrochloric acid, heating to 110 ℃ and refluxing for 12-44 hours. After the reaction is complete, a series of processing steps are carried out to finally obtain the finished product of dopamine hydrochloride. It should be sealed and stored away from light. It is usually recommended to store it under refrigeration conditions of 2-8 ℃, as it poses a certain level of danger. In case of inhalation, skin contact, or eye contact, appropriate first aid measures should be taken immediately and a doctor should be consulted. In terms of fire fighting, water mist, alcohol resistant foam, dry powder or carbon dioxide can be used to extinguish the fire.
3-Hydroxytyramine Hydrochloride CAS 62-31-7
Product Code: BM-2-5-191
Chinese name: 3-hydroxyaniline hydrochloride
CAS Number: 62-31-7
Molecular formula: C8H12ClNO2
Molecular weight: 189.64
Appearance: White or nearly white powder
EINECS Number: 200-527-8
Quality project: HPLC>98.0%,GC-MS
Product Code: 29222900
Main markets: United States, Australia, Brazil, Japan, Germany, Indonesia, United Kingdom, New Zealand, Canada, etc.
Manufacturer: BLOOM TECH Wuxi Factory
Technical Services: R&D Department-4
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What is the use of 3-hydroxytyramine hydrochloride?
3-Hydroxytyramine hydrochloride(https://en.wikipedia.org/wiki/Dopamine), also known as dopamine hydrochloride or catecholamine hydrochloride, is an important organic compound. It has a wide range of applications in multiple fields, and the following is a detailed explanation of its uses:
3-Hydroxytyramine hydrochloride is a dopamine receptor agonist that can excite the heart, increase myocardial contractility, and thus increase blood output. At the same time, it has a mild constriction effect on surrounding blood vessels and can increase arterial pressure. It has a dilating effect on visceral blood vessels such as the kidneys, mesentery, and coronary arteries, and can increase blood flow. Mainly used to treat various types of shock, including toxic shock, cardiogenic shock, hemorrhagic shock, central shock, etc. Especially for patients with renal insufficiency, decreased cardiac output, increased peripheral vascular resistance, and already replenished blood volume, the use of dopamine hydrochloride is of great significance. It can effectively improve microcirculation and protect the function of important organs.
Medical field
The commonly used dosage is intravenous infusion, 20mg at a time, and the specific dosage needs to be adjusted according to the patient's specific situation and the doctor's advice.Dopamine hydrochloride can increase myocardial contractility, improve heart function, and alleviate symptoms of heart failure. For patients with acute or chronic heart failure, especially those who do not respond well to traditional treatment drugs, dopamine hydrochloride may be an effective treatment option. It can increase renal blood flow and glomerular filtration rate, thereby promoting an increase in urine output and sodium excretion, which helps improve renal function. For patients with acute renal failure or chronic renal insufficiency, use may help reduce renal burden and promote the recovery of renal function.
3-Hydroxytyramine hydrochloride is a hydrochloride form of dopamine, which is an important neurotransmitter that plays a critical role in the nervous system. In biochemical research, dopamine hydrochloride is often used as a tool to study the physiological effects, metabolic pathways, and interactions with other biomolecules of dopamine. By studying dopamine hydrochloride, scientists can gain a deeper understanding of the function of dopamine in the nervous system and its role in the occurrence and development of neurological diseases. 3-hydroxytyramine hydrochloride plays an important role in the field of medicinal chemistry. It may be used as an intermediate or raw material for drugs, for synthesizing compounds with specific biological activities. Dopamine hydrochloride may become an important research starting point in the development of drugs for treating neurological or immune system diseases. By studying its structure and properties, scientists can design more effective drug molecules, providing new options for disease treatment.
Organic synthesis
Dopamine hydrochloride is an important organic synthetic material. Due to the presence of functional groups such as amino and hydroxyl groups in its molecular structure, it can react with various other compounds to produce products with different structures and properties. In organic synthesis, 3-hydroxytyramine hydrochloride is often used to prepare various organic compounds. For example, it can undergo neutralization reaction with alkaline substances to release corresponding amino alcohol compounds, which can then be used for subsequent chemical conversion applications. In addition, it can also participate in other types of organic reactions, such as condensation reactions, substitution reactions, etc., providing a rich source of raw materials for organic synthesis. In order to improve the synthesis efficiency and product quality of 3-hydroxytyramine hydrochloride, researchers are constantly exploring new synthesis methods. By optimizing reaction conditions and improving catalysts, researchers can increase the synthesis yield and purity of dopamine hydrochloride. Meanwhile, research on side reactions and product separation and purification techniques during the synthesis process can also help reduce production costs and improve product quality. These research findings provide strong support for the widespread application of dopamine hydrochloride in the field of organic synthesis.
Dopamine hydrochloride also has certain industrial application value. For example, it can be used as an intermediate or additive for certain chemicals to improve product performance or reduce production costs. In the dye industry, dopamine hydrochloride may be used as a synthetic raw material or adjuvant for dyes; In the plastic industry, it may be used as a modifier or stabilizer for plastics; In the pesticide industry, it may be used as a synthetic raw material or enhancer for pesticides. In addition to the aforementioned fields, dopamine hydrochloride also plays an important role in other scientific research. For example, in materials science, it can be used as a synthetic raw material or additive for certain functional materials; In environmental science, it can be used as a detection reagent or treatment agent for certain pollutants. By studying the application of dopamine hydrochloride in these fields, scientists can continuously expand its application scope and make greater contributions to the development of human society.
conclusion
3-hydroxytyramine hydrochloride, as an important bioactive substance, has shown broad application prospects in various fields such as medicine and biochemical research. With the continuous advancement of science and technology and the deepening of research, the physiological mechanism, clinical applications, and potential application areas of dopamine will be further revealed and expanded. In the future, dopamine is expected to play a greater role in anti-aging, improving athletic performance, and enhancing cognitive function. At the same time, it is necessary to strengthen research and monitoring on the safety of dopamine to ensure its safety and effectiveness in clinical applications.