Hydrazine sulfate is a salt formed by hydrazine and sulfuric acid. The molecular formula is N2H4 · H2SO4. It is colorless and tasteless scaly crystal or orthorhombic crystal. Slightly soluble in cold water, easily soluble in hot water, and the aqueous solution is acidic. Insoluble in alcohol. It is stable in the air and not easy to absorb moisture. It is a strong reducing agent. It is easy to cause explosion when encountering oxidant. Do not coexist with alkali and oxidant. Toxic and carcinogenic.
What is hydrazine sulfate used for?
1. Industrial role of hydrazine sulfate:
Azodiisobutyronitrile, etc. It can also be used as a reducing agent, mainly used as a reagent for metal surface treatment and analysis, and also for the purification of rare metals.
2. Agricultural function of hydrazine sulfate:
Used as insecticide, disinfectant, etc.
3. Pharmaceutical effects of hydrazine sulfate:
Brain tumor: Taking hydrazine sulfate and chemotherapy can improve the neurological symptoms of brain cancer patients. It may also help to reduce the tumor size of people with specific types of brain glioblastoma.
General weight loss and wasting are associated with cancer. Early studies have shown that hydrazine sulfate may slow the weight loss of some cancer patients.
Hodgkin's disease (lymphatic cancer): some studies have shown that hydrazine sulfate may slow the progression of advanced Hodgkin's disease.
Neuroblastoma (neuroblastoma): there is evidence that hydrazine sulfate may prevent the growth of neuroblastoma.
4. For preparing an Azodicarbonamide foaming agent:
It is to freeze the light hydrazine oxidation solution to 0 ~ - 10 ℃, filter and recover sodium carbonate decahydrate; Add 98% sulfuric acid dropwise to the diluted hydrazine oxidation solution after recovering sodium carbonate decahydrate to pH = 1-3, and freeze to 0 ~ - 10 ℃. After the hydrazine sulfate is completely separated, filter it while cold, and the crystallization mother liquor is applied as the water for hydrazine synthesis and several times. When the sodium chloride is saturated and begins to separate, heat the concentrated mother liquor and filter it while hot to separate sodium chloride, add water and heat to dissolve hydrazine sulfate, slowly add urea solution, and conduct condensation reaction. After the condensation reaction is completed, Cooling the feed liquid, then centrifuging the biuret, heating and concentrating the condensation mother liquid, cooling and crystallizing to obtain ammonium sulfate crystals, and the crystallization mother liquid is used as urea water distribution.
Function verification of hydrazine sulfate:
In the 1970s, it was touted as a drug for treating cancer and cachexia, but in the 1990s, it was found to be ineffective for both diseases. On the contrary, it has been shown to be carcinogenic and toxic, especially in long-term exposure.
When a person suffers from cancer or other diseases, the body will undergo a process called cachexia. In this process, the body begins to decline and the patient will experience the so-called pathological anorexia.
For cancer, this is because cancer cells absorb glucose, which is a kind of sugar that provides energy to the body. It is an inefficient substance that consumes more energy than it produces.
This causes the body to absorb additional nutrients from the excess fat reserves. This leads to the production of lactic acid, which enters the liver, where it is converted into glucose and used by cancer cells that consume energy. This is a vicious circle leading to further decline.
Dr. Joseph gold believes that hydrazine sulfate can treat cachexia and cancer because this compound has been proven to prevent the liver from converting lactic acid into glucose.
He said that this would stop the cachexia process and would effectively starve the tumor. However, in clinical trials, hydrazine sulfate did not produce any beneficial results on cancer patients.
As of 2011, hydrazine sulfate was only used in clinical trials. The US Food and Drug Administration (FDA) has not approved it for medical use, so doctors cannot prescribe this medicine.
Although hydrazine sulfate cannot be used in cancer treatment, it is used as a foaming agent in the chemical industry and is used to extract fibers from acetate fibers. It is also used as a fungicide and fungicide.
According to its material safety data sheet (MSDS), hydrazine sulfate has serious reaction in human body. The health and exposure ratings are both 3 / 4, which means that the reaction will be serious.
Contact with hydrazine sulfate is corrosive and may cause cancer if inhaled, ingested or in contact with the skin. According to MSDs, it has a slight flammability level and a moderate reactivity level.