As an essential substance of the human body, cholesterol powder exists in natural food and can be synthesized or transformed by our ability. The following is a detailed introduction to food and the body itself.
Although it exists in animal foods, its content is very different in different animals and different parts of animals. Generally speaking, the content of livestock meat is higher than that of poultry meat, fat beef is more elevated than lean meat, shells and mollusks are higher than that of ordinary fish, while the content of egg yolk, roe and animal viscera is the highest.
Human tissues contain an essential component of many biofilms except for the mitochondrial membrane and endoplasmic reticulum membrane. it is the principal sterol in the body. It is not only a necessary component of the cell membrane but also a precursor of steroid hormones, vitamin D and bile acids. The human body contains 2G of it per kilogram of body weight, and the total content of 70kg is about 140g. As early as the 18th century, it was found in gallstones. In 1816, the chemist bencher named this substance with lipid properties. widely exists in animals, especially in the brain and nerve tissue. It is also high in kidney, spleen, skin, liver and bile.it is an indispensable and essential substance in animal tissues and cells. It is involved in the formation of the cell membrane and the raw material for the synthesis of bile acids, vitamin D, and steroids. it can also be converted into bile acids, steroid hormones and 7-dehydrocholesterol after metabolism, and 7-dehydrocholesterol will be converted into vitamin D3 after ultraviolet irradiation, so it is not a substance harmful to the human body.
Cholesterol synthesis in the human body:
1. Forming formyl 3-hydroxy-3-menthyl glutarate is the first basic process of it synthesis in the human body. This process is completed in the cell fluid of the human body. Three molecules of acetyl CoA are catalyzed by thiolase and HMG-CoA synthase to achieve this process. This process is roughly the same as the formation mechanism of ketones in the human body, which is different in the internal part of the cell. This process is completed in the cell fluid; the formation of ketone bodies is conducted in the mitochondria of human hepatocytes.
2. The production of mevalonate is the second essential step of cholesterol synthesis. This step can be completed only with the catalysis of HMG CoA reductase, and the whole chemical reaction process of producing mevalonate is irreversible. In this process, HMG reductase exists as a rate-limiting enzyme of cholesterol synthesis.
3. The last process is the formation of cholesterol powder. This process requires the second step. The formed mevalonic acid goes through a series of chemical reactions, such as phosphorylation, decarboxylation, dehydroxylation, etc. most of all, after a series of redox reactions, it will eventually synthesize 27c cholesterol, which is commonly referred to as cholesterol in the body.