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Liposomal Vitamin C Syrup
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Liposomal Vitamin C Syrup

Liposomal Vitamin C Syrup

1.We supply
(1)Tablet
(2)Capsule
(3)Injection
(4)Cream
(5)Syrup
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Internal Code: BM-7-002
Ascorbic Acid CAS 50-81-7
Molecular formula: C6H8O6
Molecular weight: 176.12
EINECS number: 200-066-2
Main market: USA, Australia, Brazil, Japan, Germany, Indonesia, UK, New Zealand , Canada etc.
Analysis: HPLC, LC-MS, HNMR

 

Liposomal Vitamin C Syrup is a liquid nutritional supplement that utilizes lipid vesicle technology to sequester vitamin C in phosphatide bilayers, aiming to enhance the absorption efficiency, stability, and bioavailability of vitamin C.lipid vesicle technology enables vitamin C to bypass conventional digestion and absorption pathways and be directly released into cells through the fusion of liposomes and cell membranes.

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Manufacturing Information

This method significantly improves the absorption rate of vitamin C, and compared to traditional vitamin C supplements, the absorption efficiency can be increased several times. Vitamin C is one of the essential nutrients for the normal operation of the immune system. Liposomal vitamin C syrup can provide high concentrations of vitamin C, which helps enhance the function of the immune system and improve the body's resistance. Since lipid vesicle vitamin C syrup does not rely on digestive enzymes and transporters in the alimentary tract during absorption, it can reduce irritation to the alimentary tract and is suitable for people with alimentary sensitivity to use. It is usually used orally, and the specific dosage and frequency of use should be based on the product instructions or doctor's advice.

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What are the side effects or adverse reactions

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Stomach pain and heartburn

Reason: Although lipid vesicle VC syrup reduces direct irritation to the gastric mucosa through lipid vesicle encapsulation technology, excessive intake may still stimulate gastric acid secretion, leading to stomach pain and burning.
Symptoms: Patients may experience upper abdominal pain or burning sensation, especially when taking on an empty stomach.
Case: A patient increased the dosage on their own without following the doctor's advice, and subsequently experienced symptoms of stomach pain and burning.

Nausea Vomiting

Reason: High doses of VC may cause irritation to the alimentary tract, leading to nausea and vomiting.
Symptoms: The patient may feel nauseous and even vomit stomach contents.
Case: A child experienced nausea and vomiting after taking an overdose of Liposome-sequester vitamin C.

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Diarrhea

Reason: VC has a osmotic diuretic effect, and excessive intake may lead to an increase in intestinal water, causing diarrhea.
Performance: The patient may experience symptoms such as increased frequency of bowel movements and thin stools.
Case: Studies have shown that when the dose of vitamin C exceeds a certain threshold, the incidence of diarrhea will significantly increase. Although lipid vesicle VC syrup has a high absorption rate, excessive intake may still lead to diarrhea.

Interference with iron absorption and metabolism

Iron overload risk

Reason: V C has the effect of promoting the absorption of non heme iron, and long-term high-dose intake may interfere with the normal metabolism of iron in the body, increasing the risk of iron overload.Performance: For individuals with abnormal iron metabolism or those who require strict control of iron intake, such as those with hereditary hemochromatosis, iron overload may lead to organ damage.Case: A patient with hereditary hemochromatosis unknowingly took lipid vesicle VC syrup for a long time, leading to further increase in iron load in the body and related symptoms.

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Affects the absorption of other minerals

Reason:

High doses of VC may affect the absorption and utilization of other minerals such as copper and zinc.
Performance: Long term excessive intake may lead to a deficiency of these minerals, which in turn can cause related health problems.
Case: Although there are few specific cases, theoretically there is a possibility that requires attention.

Increased risk of kidney stones

Calcium oxalate stone risk
 

Reason:

VC is partially converted into oxalate during metabolism in the body, and excessive intake may lead to an increase in oxalate levels in urine, thereby increasing the risk of kidney stones, especially calcium oxalate stones.

Performance:For individuals with a history of kidney disease or a family history of kidney stones, the risk may be higher. The patient may experience symptoms such as lower back pain and hematuria.Case:A study has found that supplementing with more than 1000mg of VC daily may increase the risk of kidney stones in men. 

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impaired renal function

 

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Reason:

Long term excessive intake of VC may cause a burden on the kidneys and lead to kidney function damage.
Symptoms:

Patients may experience decreased urine output, darkened urine color, and in severe cases, may even lead to kidney failure.
Case:Although this situation is relatively rare, there are still reports indicating that patients may experience kidney function impairment after long-term and excessive use of VC.

Rash and itching

Reason: Some people may be allergic to VC or lipid vesicle components, causing rash and itching.
Symptoms: The patient's skin may develop rashes such as erythema and papules, accompanied by itching.

Breathing difficulties

Reason: Severe allergic reactions may cause respiratory edema, leading to difficulty breathing.
Symptoms: Patients may feel shortness of breath, chest tightness, and even suffocation.

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Drug interactions

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Affects the efficacy of anticoagulant drugs

Reason: High doses of VC may weaken the effectiveness of anticoagulant drugs (such as warfarin) and increase the risk of blood clots.
Performance: The patient may experience abnormal coagulation function, such as prolonged clotting time.
Case: A patient taking warfarin experienced symptoms of coagulation dysfunction after increasing the dose of liposomal vitamin C syrup on their own.

Interference with the action of chemotherapy drugs

Reason: VC may interfere with the efficacy of some chemotherapy drugs, affecting the treatment outcome.
Performance: The patient may experience poor chemotherapy efficacy or disease progression.
Case: Although there are few specific cases, theoretically there is a possibility that requires the attention of doctors and patients.

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Other potential side effects

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Potential risks of long-term excessive intake-Reduce immunity: Although VC has immunomodulatory effects, long-term excessive intake may disrupt the balance of the immune system in the body, leading to a decline in immunity.Impact on blood glucose monitoring: large doses of vitamin C may interfere with blood glucose monitoring results (such as urine glucose test paper method), which needs special attention for diabetes patients.Case: Studies have shown that people who take large amounts of VC for a long time may not have a reduced risk of contracting certain diseases, and may even have a slight upward trend. 

Headache and dizziness-Reason:

Excessive intake of VC may cause changes in blood osmotic pressure, leading to headaches and dizziness.
Symptoms:

The patient may experience head swelling or dizziness.A patient experienced symptoms of headache and dizziness after taking excessive amounts of Liposome-sequester VC.

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Method of Analysis

 

Particle Size Analysis Method

Liposomal Vitamin C Syrup is a novel formulation that sequester VC in lipid vesicle, and liposome technology can improve the stability and bioavailability of VC. Accurate analysis of lipid vesicle vitamin C syrup is of great significance for ensuring product quality, controlling production processes, and evaluating its efficacy and safety. The following is its analysis method:

Liposomal Vitamin C Particle  | Shaanxi BLOOM Tech Co., Ltd

Liposomal Vitamin C Method | Shaanxi BLOOM Tech Co., Ltd

Liposomal Vitamin C Analysis | Shaanxi BLOOM Tech Co., Ltd

 

 

(1)Dynamic Light Scattering Method (DLS)

Principle
The dynamic light scattering method is based on the Brownian motion of particles in a liquid, and calculates the particle size by measuring the fluctuation of scattered light intensity. When laser is irradiated onto particles, scattering occurs. Due to the Brownian motion of particles, the intensity of scattered light fluctuates over time. By analyzing these fluctuation signals through correlation functions, the diffusion coefficient of particles can be obtained, and the particle size can be calculated according to the Stokes Einstein equation.


Experimental procedure
Sample preparation: Dilute the liposome VC syrup sample with an appropriate solvent (such as distilled water, phosphate buffer solution, etc.) to the appropriate concentration to avoid particle interactions and multiple scattering phenomena.
Instrument operation: Add the diluted sample to the sample pool, place it in the dynamic light scattering instrument, set appropriate measurement parameters (such as measurement time, angle, etc.), and start the instrument for measurement.
Data analysis: The instrument will automatically analyze and process the measurement data, providing information.


Advantages and disadvantages
Advantages: The dynamic light scattering method is easy and fast to operate, and can monitor the particle size changes in real time; The concentration requirement for the sample is relatively low, suitable for particle size analysis of various dispersion systems.
Disadvantages: This method has high requirements for particle shape, assuming that the particles are spherical, there may be some errors in the measurement results for non spherical particles; In addition, the particle size measured by dynamic light scattering method is the hydrated particle size, which may differ from the actual dry particle size of the particles.

 

(2)Laser particle size analysis method
Principle
Laser particle size analysis method uses the scattering phenomenon of particles on laser to measure the particle size distribution of particles. When the laser is irradiated onto the particle group, the particles will scatter the laser, and the angle and intensity of the scattered light are related to the particle size. By measuring the scattered light intensity at different angles and using Mie scattering theory or other related theories for calculation, the particle size distribution can be obtained.

 

In the realm of nutritional supplements, few innovations have sparked as much interest as liposomal technology. This advanced delivery system, which encases nutrients in microscopic lipid spheres, has transformed how the body absorbs and utilizes key vitamins. Among these breakthroughs, Liposome-sequester VC stands out as a game-changer, offering unparalleled bioavailability, immune support, and therapeutic potential.

FAQ 

For what is VC good for?

VC is a substance the body needs to form blood vessels, cartilage, muscle and collagen in bones. The body also needs vitamin C for healing. Also called ascorbic acid, VC helps protect cells from damage. Substances like vitamin C that protect against cell damage are called antioxidants.

Should you take vitamin C daily?

In general, experts recommend that women get 75 mg of vitamin C a day and men get 90 mg. Pregnant people should aim to get 85 mg a day.

What are the symptoms of low vitamin C?

Patients might present with fatigue, malaise, lethargy, and anorexia. [9] Subsequently, patients with scurvy experience oral and skin symptoms such as bleeding gums, easy bruising, skin rashes, fragility, delayed wound healing, and bone and joint aches.

What is the best time to take vitamin C?

The morning.When should vitamin C be taken? The best time to take vitamin C is on an empty stomach. This means taking it in the morning, 30 minutes before a meal, or two hours after eating. Vitamin C is a water-soluble vitamin, making it easy for the body to absorb.

 

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