Methyl sulfone powder(Dimethyl sulfone) is an organic sulfide compound commonly referred to as MSM (Methylsulfonylmethane). It typically appears as a white crystalline powder, odorless or with a slight characteristic odor.It is easily soluble in polar solvents such as water, ethanol, and acetone, and slightly soluble in non-polar solvents. It is stable at room temperature and pressure, but may decompose under high temperature or strong oxidation conditions. MSM is naturally present in the human body and participates in the synthesis of important substances such as collagen and keratin.
It is beneficial for skin, hair, bones, and joint health, and has the effect of reducing oxidative stress and inflammatory reactions. It may help alleviate joint pain and improve motor function. It is often added to skincare products to improve skin elasticity and radiance due to its ability to promote collagen production. Simultaneously used as a plant nutrient supplement in agriculture and as a high boiling point solvent or reaction intermediate in industry. It is sold globally in the form of dietary supplements, commonly in capsules, powders, or topical formulations.
At the same time, our company not only provides pure powders, but also tablets and injections. If needed, please feel free to contact us at any time.
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Additional information of chemical compound:
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Product Name |
Methyl sulfone Powder |
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Product Type |
Powder |
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Product Purity |
100g/1kg/etc. |
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Product Form |
Organic synthesis |
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Methyl Sulfone COA
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| Certificate of Analysis | ||
| Compound name | Methyl Sulfone | |
| Grade | Pharmaceutical grade | |
| CAS No. | 67-71-0 | |
| Quantity | Customized | |
| Packaging standard | Customized | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
| Lot No. | 202601090088 | |
| MFG | Jan 9th 2026 | |
| EXP | Jan 8th 2029 | |
| Structure |
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| Item | Enterprise standard | Analysis result |
| Appearance | White or almost white powder | Conformed |
| Water content | ≤5.0% | 0.34% |
| Loss on drying | ≤1.0% | 0.16% |
| Heavy Metals | Pb≤0.5ppm | N.D. |
| As≤0.5ppm | N.D. | |
| Hg≤0.5ppm | N.D. | |
| Cd≤0.5ppm | N.D. | |
| Purity (HPLC) | ≥99.0% | 99.80% |
| Single impurity | <0.8% | 0.45% |
| Total microbial count | ≤750cfu/g | 70 |
| E. Coli | ≤2MPN/g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (by GC) | ≤5000ppm | 400ppm |
| Storage | Store in a sealed, dark, and dry place below 30°C | |
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| Chemical Formula | C2H6O2S |
| Exact Mass | 94.01 |
| Molecular Weight | 94.13 |
| m/z | 94.01 (100.0%), 96.00 (4.5%), 95.01 (2.2%) |
| Elemental Analysis | C, 25.52; H, 6.43; O, 33.99; S, 34.06 |
Methyl sulfone Powder is an organic sulfide with the chemical formula C ₂ H ₆ O ₂ S, which has a wide range of applications in various fields. It plays an important role in various industries such as human health, food, medicine, industry, daily chemical products, and feed. The following is a detailed description of its purpose:
Application in the field of human health and health products
Dimethyl sulfone is an essential substance for human collagen synthesis. MSM is present in human skin, hair, nails, bones, muscles, and various organs. Collagen is one of the most abundant proteins in the human body, providing elasticity and firmness to the skin, maintaining bone and joint health, and making hair and nails tough and shiny. Dimethyl sulfone participates in the synthesis of collagen by providing nutrients such as sulfur, ensuring that the human body can synthesize and renew collagen normally, thereby maintaining the normal structure and function of various tissues in the body.
The human body consumes about 0.5mg of MSM per day, and once lacking, it may cause health disorders or diseases. Dimethyl sulfone is the main substance that maintains the balance of sulfur elements in human biology. Sulfur is involved in various physiological processes in the human body, such as protein synthesis and enzyme activity regulation. The organic sulfur in dimethyl sulfoxide can supplement the human body's demand for sulfur, maintain a stable level of sulfur in the body, and ensure the normal functioning of various physiological functions.
Dimethyl sulfone is a source of glutathione antioxidant sulfur. Glutathione is an important antioxidant that can eliminate oxygen free radicals in the human body. Oxygen free radicals are highly reactive molecules that can cause damage to human cells and tissues, leading to problems such as aging and disease. Dimethyl sulfone enhances the body's antioxidant capacity by providing sulfur, promoting the synthesis of glutathione, reducing the damage caused by oxygen free radicals, and protecting cells and tissues from oxidative stress.
Research has shown that dimethyl sulfoxide has good anti-inflammatory activity. It can significantly inhibit the secretion of inflammatory factors such as IL-17F, IL-23, and TNF - α, while enhancing the expression of anti-inflammatory factor IL-22. Inflammation is one of the pathogenesis mechanisms of many diseases, such as arthritis, cardiovascular disease, etc. The anti-inflammatory effect of dimethyl sulfoxide can help alleviate inflammatory reactions, alleviate pain and discomfort caused by inflammation, and prevent and alleviate the occurrence and development of related diseases.
Methyl sulfone powder can enhance the ability of the human body to produce insulin and promote the metabolism of carbohydrates. Insulin is an important hormone that regulates blood sugar levels. It can promote the uptake and utilization of glucose by cells and reduce blood sugar concentration. Dimethyl sulfone enhances insulin synthesis and secretion, increases cell sensitivity to insulin, thereby improving carbohydrate metabolism and helping to maintain blood sugar stability.
This is of great significance for the prevention and treatment of glucose metabolism disorders such as diabetes. It can promote wound healing. It can increase water binding and help repair damaged cartilage and other tissues. During the wound healing process, dimethyl sulfoxide can promote cell proliferation and migration, accelerate tissue repair and regeneration. Meanwhile, its antioxidant and anti-inflammatory effects also help reduce wound infections and inflammatory reactions, creating a favorable environment for wound healing.
This substance is one of the main sources of sulfur for the synthesis of methionine, cysteine, sulfur-containing peptides, proteins, and sulfur-containing tissues in the body. 85% of the sulfur in the sulfur-containing tissues of living organisms is supplied by dimethyl sulfoxide and dimethyl sulfoxide homologues. These sulfur-containing substances are crucial for maintaining the normal function of the immune system.
They participate in the synthesis of immunoglobulin, which is an important component of the immune system that can recognize and eliminate pathogens in the body. By providing sulfur, it can promote the production of immunoglobulin, enhance the body's immunity, and improve the body's resistance to diseases. Dimethyl sulfone, as a food grade ingredient, has a whitening effect on the skin. It can inhibit the production of melanin, reduce the formation of pigmentation, and make the skin fairer.
Meanwhile, dimethyl sulfoxide has excellent moisturizing properties, which can increase the moisture content of the skin, maintain its hydration and elasticity, and make the skin look smoother and healthier. Due to its antioxidant properties, it can reduce the damage of free radicals to the skin and delay the aging process of the skin. Free radicals can damage collagen and elastin fibers in the skin, leading to problems such as sagging and increased wrinkles. Dimethyl sulfone helps maintain the youthfulness of the skin by scavenging free radicals, protecting skin cells and tissues.
Benefits for Joint Health
Arthritis is mainly characterized by degenerative changes in articular cartilage and secondary bone hyperplasia. The mucous membrane at the joint junction is composed of sulfur-containing proteins and glucosamine. Dimethyl sulfone can promote the production of collagen, increase water binding, and help repair damaged cartilage.Meanwhile, its anti-inflammatory effect can alleviate joint inflammation, thereby relieving joint pain.
Many arthritis patients have experienced significant relief of joint pain after using health supplements containing dimethyl sulfoxide. Dimethyl sulfone can improve joint function by promoting cartilage repair and regeneration. It can increase joint flexibility and range of motion, reducing joint stiffness and limited mobility. For some patients with mobility difficulties caused by joint diseases, the application of dimethyl sulfoxide can improve their quality of life.
The effect on the digestive system
Supplementing MSM in diet can prevent gastrointestinal diseases. It can regulate the balance of gut microbiota, inhibit the growth of harmful bacteria, and promote the proliferation of beneficial bacteria. Meanwhile, the anti-inflammatory and antioxidant effects of dimethyl sulfoxide can protect the intestinal mucosa and reduce the occurrence of intestinal inflammation and damage. Long term use of dimethyl sulfoxide can enhance gastrointestinal function. It can promote the secretion of digestive juices, improve the peristalsis ability of the gastrointestinal tract, and aid in the digestion and absorption of food. For some people with indigestion and weak gastrointestinal function, dimethyl sulfoxide can have a certain improvement effect.
Methyl sulfone Powder, with the chemical formula (CH3)2SO2, is industrially produced mainly by oxidizing dimethyl sulfoxide (DMSO). The dominant synthesis routes include nitric acid oxidation, hydrogen peroxide oxidation and microchannel continuous flow processes, which are elaborated as follows.
Nitric Acid Oxidation (Traditional Industrial Route)
This process uses DMSO as the raw material and concentrated nitric acid as the oxidant. The chemical reaction equation is: (CH3)2SO + 2HNO3 → (CH3)2SO2 + 2NO2↑ + H2O
DMSO is heated to 90–100 °C, followed by slow dropwise addition of concentrated nitric acid at a molar ratio of 1:1.88. The reaction temperature is strictly controlled at 140–145 °C to avoid bumping.
The reaction releases substantial heat, so a condenser is applied for reflux. The nitrogen dioxide (NO2) tail gas is regenerated with oxygen for recycling.
After the reaction completes, the mixture is cooled with ice brine for crystallization, and crude product is obtained by filtration. Purification is conducted via vacuum distillation (138–145 °C / 740 mmHg) or recrystallization, yielding a product purity of 99%.
Though technically mature, this process causes severe pollution and entails high costs for waste acid and NO2 treatment, and is gradually phased out in favor of eco-friendly technologies.
Hydrogen Peroxide Oxidation (Mainstream Green Process)
DMSO is oxidized by hydrogen peroxide (H2O2), with only water and oxygen generated as by-products, delivering high atom economy. In the conventional procedure, DMSO is heated to 90–100 °C, and 27.5%–50% hydrogen peroxide solution is added dropwise.
The mixture undergoes reflux reaction for 3 to 5 hours at a molar ratio of DMSO to H2O2 of 1:1.2–1.5. 2,6-naphthalenedicarboxylic acid can be used as a catalyst to achieve a conversion rate of ≥96% and selectivity of ≥99%, which simplifies subsequent purification.
Post-reaction treatment includes cooling and crystallization, decolorization with activated carbon, desalination via ion exchange and vacuum drying, producing a final product with purity up to 99.9%.
Featuring high safety and low toxicity along with mild product odor, this is currently the dominant production technology.
Microchannel Continuous Flow Synthesis (Advanced Intensified Process)
To address the severe exothermic risk of hydrogen peroxide oxidation, a microchannel reactor is adopted. The reaction is performed at a precisely controlled temperature of 120–130 °C with a residence time of 10 minutes.
A 50% hydrogen peroxide solution is used at a molar ratio of 1:1.5, achieving full conversion of DMSO. The microchannel reactor enables efficient heat and mass transfer, eliminating local overheating and thermal runaway.
It also features low material hold-up and superior safety. Continuous operation shortens production cycles, boosts capacity by over 30%, and delivers a stable product purity of ≥99.5%, making it suitable for large-scale green manufacturing.
Other Auxiliary Methods
Ultraviolet Oxidation: Oxygen is irradiated by ultraviolet light and then introduced into DMSO solution for oxidation and crystallization at ambient temperature. This method consumes low energy but suffers from low efficiency, and is only applied for laboratory-scale trials.
FAQ
What drug is dimethyl sulfone?
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Dimethyl Sulfone is being used as a cutting agent, or diluent, in the illicit manufacture of methamphetamine.
Is dimethyl sulfone toxic?
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Based on the data available from the test chemical, Dimethyl sulfone, methanesulfonylmethane (67-71-0) not likely to exhibit repeated dose oral, dermal and inhalation toxicity.
Is dimethyl sulfone the same as MSM?
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MSM is also known as dimethyl sulfone, crystalline DMSO, DMSO2 or Vibrant Life. WHAT IS DMSO USED FOR? DMSO is primarily used as an industrial solvent for things such as paint thinners. It is definitely not an essential nutrient and is not required for the functioning of a healthy body.
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