Announcement
This chemicals was banned to sell, our website only can check the basic info. of chemicals here, we don't sell them!
April 17, 2024
1. Quality
We achieved it in 2021; We don't sell it to Chinese resellers. It can protect your purchasing resource and our stable supplement. We don't want the Unrelated sellers involved in the core business.
2. Market
(1)This product requires extremely high organic synthesis ability and is challenging. In addition, More than 90.0% of R&D companies cannot succeed due to the great difficulty.
(2)It is a fake phenomenon: There are many suppliers anywhere you find on the web. For these "suppliers," the majority of them, the company comprises only one person of himself. After he cheats many payments, fake products, and fake shipping promises will establish a new company.
(3)They don't have a scientific analysis result, such NMR, LCMS, HPLC, etc... They don't know anything about chemistry; they just use sensitive words to attract buyers.
3. Analogue
To become our satable buyers, one for one service. For researching only.
The design of the tablet pressing die not only requires proper coordination, coordination, and selection, but also ensures the safe export of the formed tablets. However, the die manufacturing is very crucial to maintain its accuracy and quality. Using vacuum heat treatment technology on die production, Achieve Chem is able to increase die's durability to reduce production cost of users. With sincerity and reliability, Achieve Chem has gradually accumulated users both domestically and internationally.
|
|
|
|
|
Chemical Formula |
C21H26N4O3 |
|
Exact Mass |
382 |
|
Molecular Weight |
382 |
|
m/z |
382 (100.0%), 383 (22.7%), 384 (2.5%), 383 (1.5%) |
|
Elemental Analysis |
C, 65.95; H, 6.85; N, 14.65; O, 12.55 |
We are the supplier of N-Desethyl-Isotonitazene.
Remark: BLOOM TECH(Since 2008), ACHIEVE CHEM-TECH is our subsidiary of us.
|
|
|
We can provide this product on HPLC>98.0%, if you need the accurate information, pls contact our sales. We can share our analysis result, negotiate the free sample, provide a professional quotation etc.
It is a synthetic drug that is a derivative of the fentanyl class of drugs. It is a strong opioid pain reliever with analgesic and sedative effects.
Although it is used for medical purposes in some countries, it is classified as an illegal drug elsewhere. Due to its highly addictive and dangerous nature, it is considered a serious drug abuse risk.
Therefore, as an AI language model, I would not recommend or support the use of N-Desethyl-Isotonitazene. Consult a qualified healthcare professional if you require any form of medical or drug treatment.
N-Desethyl Isotonitazene is a synthetic opioid like compound that is one of the metabolites of Isotonitazene.
1. Molecular formula: C16H18N2O2
-C represents carbon, H represents hydrogen, N represents nitrogen, and O represents oxygen.
-The number in the molecular formula represents the number of atoms, indicating that the molecule contains 16 carbon atoms, 18 hydrogen atoms, 2 nitrogen atoms, and 2 oxygen atoms.
2. Structural diagram:
-The structure of N-Desethyl Isotonitazene can be seen as consisting of two parts, namely a pyrimidine ring and a styrene side chain.
-The pyrimidine ring contains 4 carbon atoms and 2 nitrogen atoms, forming a six membered ring.
-The styrene side chain is connected to a carbon atom on the pyrimidine ring, containing 8 carbon atoms and 1 oxygen atom.
3. Carbon atom connection:
-On the pyrimidine ring, the first carbon atom is connected to a nitrogen atom, forming a carbon nitrogen double bond.
-The second and fourth carbon atoms are connected together to form a carbon carbon single bond.
-The third carbon atom is connected to the second nitrogen atom, forming a carbon nitrogen double bond.
-The structure formed by carbon atoms results in a flattened geometric configuration of the pyrimidine ring.
4. Oxygen atom connection:
-On the side chain of styrene, an oxygen atom is connected to the fourth carbon atom through a carbon oxygen single bond.
-The carbon oxygen bond formed by oxygen atoms and carbon atoms is a polar covalent bond.
5. Molecular properties:
-N-Desethyl Isotonitazene belongs to opioid like compounds and may have analgesic and anesthetic effects in living organisms.
-The pyrimidine ring and styrene side chain in its molecular structure endow it with pharmacological activity.
-The oxygen atoms in molecules may have an impact on their solubility, stability, and interactions with other substances.
N-Desethyl-Isotonitazene (also known as Desethyllunitrazepam) belongs to the benzodiazepine family of drugs, which includes many compounds with sedative, hypnotic, and anti anxiety properties.
1. Benzodiazepines: N-Desethyl Isotonitazene is a derivative of benzodiazepines. Benzenediazepines are widely used drugs, including sedative hypnotics, Anxiolytic and anticonvulsants. They enhance neurotransmitters γ- The inhibitory effect of aminobutyric acid (GABA) in the central nervous system leads to pharmacological effects.
2. Azide heterocyclic compounds (Tetrazoles): The chemical structure of N-Desethyl Isotonitazene contains two azide heterocycles (Tetrazoles rings). Azide heterocycles are five membered heterocycles composed of four nitrogen atoms, which are common in the pharmaceutical field and have a wide range of biological activities.
3. Derivatives of benzodiazepines: it is obtained by removing the Acetyl group group from the benzodiazepines drug Fluunitrazepam (also called Rohypnol). Fluunitrazepam is a powerful sedative and hypnotic drug commonly used in short-term treatment and preoperative sedation in medical practice.
4. Structure activity relationship: The structure and functional characteristics of N-Desethyl Isotonitazene may have similarities and differences with other benzodiazepine drugs. The structure of benzodiazepines can be modified to change their activity, selectivity and pharmacokinetics. Therefore, research on similar compounds can help to gain a deeper understanding of their interactions with the nervous system and potential pharmacological properties.
Abuse and harm
N-Desethyl-Isotonitazene (a highly active synthetic opioid) belongs to the 2-phenylmethyl benzimidazole class. Its potency is approximately 20 times that of fentanyl. In recent years, the emergence of this substance in the illegal drug market has caused serious public health problems. The abuse of this substance and its harmful effects cannot be ignored.
 |
 |
 |
Abuse situation
N-Desethyl-Isotonitazene was initially discovered as a metabolite of isotonitazene, but it has now become a separate type of new psychoactive substance in circulation. Its forms of abuse are diverse, commonly found in counterfeit drugs, illegal drug mixtures, and entertainment venues. This substance often exists in powder form and may be compressed into pills or mixed with other substances such as heroin, fentanyl analogues, or benzodiazepines to enhance effects or reduce costs. Abusers consume it by oral intake, nasal inhalation, injection, or inhalation. Among these, injection and nasal inhalation are more favored due to their rapid onset, but this also significantly increases health risks.
In the illegal drug market, the circulation of N-Desethyl-Isotonitazene is often associated with underground laboratories and transnational drug trafficking networks. Its production process is simple and the raw materials are readily available, enabling the rapid spread of this substance worldwide. Moreover, the anonymity and convenience of online platforms provide a breeding ground for its illegal transactions, further exacerbating the severity of the abuse problem.
Health hazards
N-Desethyl-Isotonitazene, as a potent μ-opioid receptor agonist, can cause a series of serious health problems when abused. Acute poisoning symptoms include respiratory depression, coma, constricted pupils, muscle rigidity, and loss of consciousness, and in severe cases, it can lead to respiratory failure and death. Its potency is far greater than that of traditional opioid drugs such as morphine and heroin, so even a small intake can result in fatal consequences.
Long-term abuse of N-Desethyl-Isotonitazene can lead to physical dependence and psychological dependence. Physical dependence is manifested by increased tolerance and withdrawal symptoms, such as anxiety, insomnia, muscle pain, nausea, vomiting, and diarrhea. Psychological dependence is characterized by a strong craving and compulsive drug use behavior, even when the user is aware of the dangers and finds it difficult to control themselves. Moreover, this substance may also cause mental symptoms, such as hallucinations, delusions, and aggressive behavior, further exacerbating social harm.
Social Impact
The abuse of N-Desethyl-Isotonitazene not only poses a threat to individual health, but also has a profound impact on society. Its high fatality rate leads to a strain on medical resources and increases the burden on public health. At the same time, the abuse behavior is closely related to criminal activities, such as theft, robbery, and violent crimes, which undermine social stability and security. Moreover, the illegal circulation of this substance also promotes the spread of organized crime, posing a potential threat to national security.
Regulation and Response
Given the severe harmfulness of N-Desethyl-Isotonitazene, governments around the world have taken a series of measures to strengthen supervision. For instance, China has included it in the "Supplementary Catalogue of Controlled Substances for Non-Pharmaceutical Anesthetic Drugs and Psychotropic Substances", and it will be subject to control as of July 1, 2024. The United Nations Commission on Narcotic Drugs has also, in accordance with the recommendations of the World Health Organization, classified it as an international controlled substance, recognizing that it has the potential to cause serious harm or death and has no known medical uses.
However, the implementation of regulatory measures still faces challenges. The concealment and transnational nature of the illegal drug market make it difficult to completely eradicate the circulation of this substance through crackdowns. Therefore, strengthening international cooperation, raising public awareness, and improving the detoxification treatment system have become the key to addressing the abuse of N-Desethyl-Isotonitazene.
Hot Tags: N-Desethyl-Isotonitazene CAS 2732926-24-6, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale, larocaine hydrochloride, 1 3 dimethylpentylamine hydrochloride, procaine powder, tetrahydrobiopterin synthesis, pontocaine, levamisole hydrochloride powder