Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of uvinul mc 80 cas 5466-77-3 in China. Welcome to wholesale bulk high quality uvinul mc 80 cas 5466-77-3 for sale here from our factory. Good service and reasonable price are available.
Uvinul mc 80(Octyl 4-methoxycinnamate), also known as octinoxate (USAN name), Eusolex2292, UvinolMC80 (trade name). CAS 5466-77-3, Molecular formula C18H26O3, orange yellow oily transparent liquid. Boiling point 216 ℃ (0.133-0.267kpa), refractive index 1.535 (26 ℃). Soluble in ethanol, insoluble in water. It is an organic compound used in some sunscreen products, lipstick and other beauty products to absorb UVB in the sun and protect the skin from damage. It is the most commonly used UVB sunscreen. It is a transparent liquid that is insoluble in water at room temperature. Isooctyl methoxycinnamate is one of the most commonly used sunscreen agents in the world. It has a UV absorption curve of 280-310 nm, high absorption rate, good safety, minimal toxicity, and good solubility in oily materials. Therefore, it is widely used in daily chemical, plastic, rubber, and coating industries. As an oil soluble liquid UV-B absorber, it can be compounded with various sunscreen agents.

|
Chemical Formula |
C18H26O3 |
|
Exact Mass |
290 |
|
Molecular Weight |
290 |
|
m/z |
290 (100.0%), 291 (19.5%), 292 (1.8%) |
|
Elemental Analysis |
C, 74.45; H, 9.02; O, 16.53 |
|
|
|

Octyl 4-methoxycinnamate(Uvinul mc 80), also known as Octinoxate (USAN name), Eusolex2292, UvinolMC80 (trade name), is an important organic compound with the chemical formula C18H26O3 and CAS number 5466-77-3. It has many unique physical and chemical properties, such as being a transparent liquid insoluble in water at room temperature and having good solubility for oily raw materials. With these characteristics, it plays a crucial role in multiple fields.
Daily chemical industry
(1) Sunscreen products
Sunscreen and lotion: It is the core ingredient of sunscreen and lotion. It can efficiently absorb UVB ultraviolet rays in the 280-310nm wavelength range, with maximum absorption occurring at 311nm. This characteristic enables it to effectively prevent human skin from being sunburned, sunburned, and tanned. In high magnification sunscreen with SPF50+, the dosage is usually controlled between 5% and 10%. By adding such a ratio, it can work synergistically with other sunscreen ingredients to provide reliable protection for the skin. For example, when combined with UVA absorbers such as avobenzone and oak, it can form a broad-spectrum sunscreen system that comprehensively resists the damage of ultraviolet rays to the skin.
Lipstick: The cuticle of the lip skin is thin, and it is more vulnerable to UV damage. It is widely used in lipstick and can form a transparent protective film on the lips. This protective film can effectively reduce the damage of ultraviolet rays to the lips, and lower the likelihood of lip dryness, cracking, pigmentation, and other issues. Its oil solubility makes it compatible with the grease matrix in lipstick, and will not affect the use feeling and texture of lipstick.
Makeup products: They also play an important role in liquid foundation, isolation cream and other cosmetics products. It can provide basic sun protection for the skin, allowing users to receive some UV protection while applying makeup. Moreover, due to its good compatibility with oil-based substrates, it does not affect the extensibility and makeup effect of cosmetic products, allowing the skin to have a beautiful makeup look while also being protected.


Assisted treatment of photosensitive dermatitis
Clinical studies have shown that it has an adjuvant therapeutic effect on photosensitive skin diseases. It can absorb ultraviolet energy, thereby reducing the sensitivity of the skin to light. During the acute phase of photodermatitis, medical skincare products containing this substance can alleviate symptoms such as erythema and edema. Some medical skincare products combine it with anti-inflammatory ingredients (such as dipotassium glycyrrhizinate) to effectively care for the skin of patients with photodermatitis and promote skin recovery through the synergistic effect of multiple ingredients.
Industrial sector
(1) Plastic products
Outdoor plastic sheet: It is commonly used as a light stabilizer in general plastics such as polyethylene and polypropylene. It absorbs ultraviolet energy and converts it into thermal energy for release, thereby avoiding problems such as yellowing and brittleness caused by polymer molecular chain breakage. Adding 0.5% -1% octyl methoxycinnamate to outdoor plastic sheets can extend the service life of the material by 2-3 times. This has important economic significance and practical value for plastic sheets used in outdoor buildings, billboards, and other applications.
Other plastic products: In addition to outdoor plastic sheets, they are also added to many other plastic products. For example, adding this ingredient to some outdoor furniture, plastic containers, etc. can improve their durability in outdoor environments, reduce aging caused by ultraviolet radiation, and maintain the appearance and performance of the product.
(2) Ink and Coatings
Printing ink: It plays an important role in UV ink. It can absorb scattered ultraviolet rays during the curing process, reducing the aging of the ink layer. This helps maintain the color brightness and adhesion of the ink, improving the quality and durability of printed materials. For some products that require high printing quality, such as high-end packaging, advertising posters, etc., using UV ink containing this substance can ensure that it maintains good visual effects during long-term display.
(3) Rubber products
Tires: Tires are exposed to outdoor environments and are exposed to ultraviolet radiation during driving. Inhibiting the free radical chain reaction induced by ultraviolet radiation in tires delays the cross-linking and degradation of rubber molecular chains. Synergistic effect with antioxidant 4020 can improve the ozone aging resistance of tires by more than 50%. This helps to extend the service life of tires, improve their safety and reliability, and reduce the frequency and cost of tire replacement.
Sealing strip: Sealing strips are commonly used in doors, windows, cars, and other parts, requiring a certain degree of weather resistance. Adding octyl methoxycinnamate can improve the UV resistance of the sealing strip, prevent it from hardening and cracking due to UV irradiation, thereby ensuring the sealing effect and extending the service life of the sealing strip.
Medical field
(1) Research on the regulatory effect of hormones
Partial in vitro experiments have shown that uvinul mc 80 may have weak estrogen like activity, with a binding affinity to estrogen receptors (ER) of approximately 1/1000 that of estradiol. However, no significant endocrine disrupting effects were observed in animal experiments. The FDA classifies it as a "Generally Recognized as Safe" (GRAS) substance, but the European Scientific Committee on Consumer Safety (SCCS) still recommends that its maximum concentration for use in cosmetics should not exceed 10%. This indicates that under normal usage, the impact on the human hormone system is relatively small, but still requires certain supervision and restrictions.
(2) Carrier materials for drug delivery systems
In recent years, its lipophilicity has led to its research for transdermal drug delivery systems. Through microemulsification technology, it can form nanoscale complexes with drug molecules, improving the skin permeability of insoluble drugs. For example, in transdermal patches of nonsteroidal anti-inflammatory drugs (such as diclofenac), adding this substance can increase the cumulative drug penetration by 30% to 50%. This provides new ideas and methods for developing novel transdermal drug delivery formulations, which can help improve the efficacy of drugs and the convenience of medication for patients.
(3) Antibacterial and anti-inflammatory activity
In vitro antibacterial experiments have shown that it has a certain inhibitory effect on pathogenic bacteria such as Propionibacterium acnes and Staphylococcus aureus, with a minimum inhibitory concentration (MIC) between 100-500 μ g/mL. In addition, it can reduce the release of inflammatory factors (such as TNF - α and IL-6) induced by lipopolysaccharides by inhibiting the NF - κ B signaling pathway. This provides a theoretical basis for the development of anti-inflammatory skincare products, and in the future, more skincare products containing this substance with antibacterial and anti-inflammatory effects may be developed to meet consumers' needs for skin health.
Other potential uses
(1) Flexible electronic devices
With the development of flexible electronic devices, it has been studied as a UV shielding material for the packaging layer of OLED displays. It can form a dense thin film through vacuum evaporation technology, reducing the ultraviolet transmittance to below 0.1% while maintaining high transmittance (>90%). This helps to protect the organic materials inside OLED displays from UV damage, extend the lifespan of the display, and improve its performance and stability.
(2) In the field of agriculture
In the agricultural field, it is added as a light stabilizer to agricultural film. It can extend the service life of plastic film and reduce "white pollution". Traditional agricultural film is prone to aging and cracking under ultraviolet radiation, resulting in a shortened service life and generating a large amount of waste film, which pollutes the environment. After addition, the weather resistance of the plastic film is improved, which can better exert its insulation, moisturizing and other functions, while reducing the negative impact on the environment.
Uvinul mc 80 has important applications in various fields such as daily chemical, industrial, and pharmaceutical industries. Although it has some potential environmental and health risks, its application safety can be effectively guaranteed through reasonable formula design, process optimization, and regulatory supervision. In the future, with the continuous development and innovation of technology, octyl methoxycinnamate is expected to play a greater role in more fields.
It remains indispensable in modern sun care due to its unmatched efficacy, formulation versatility, and regulatory compliance. However, environmental concerns necessitate a dual approach: optimizing existing formulations through stabilization technologies while accelerating research into sustainable alternatives. The industry's future lies in developing hybrid systems that balance human protection with ecological preservation, exemplified by BASF's 2025 launch of "EcoSun MC80" containing 70% bio-based content. As regulatory pressures intensify, manufacturers must prioritize green chemistry principles to maintain market leadership in the evolving sun care landscape.
Hot Tags: uvinul mc 80 cas 5466-77-3, suppliers, manufacturers, factory, wholesale, buy, price, bulk, for sale, L Selenomethionine powder, SYN AKE powder, 4 Butylresorcinol powder, 4-Butylresorcinol powder, PERFLUOROOCTYL TRIETHOXYSILANE







