Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of 5-iodoindole cas 16066-91-4 in China. Welcome to wholesale bulk high quality 5-iodoindole cas 16066-91-4 for sale here from our factory. Good service and reasonable price are available.
5-Iodoindole is an important organic heterocyclic compound. Its structure is centered around indole - that is, a benzene ring and a pyrrole ring are fused together, and an iodine atom is connected to the fifth carbon atom of the pyrrole ring through a stable carbon-iodine bond. This key modification endows the molecule with both aromaticity and the reactivity of a halide compound, presenting as a light yellow to off-white crystalline powder. It is stable at room temperature but requires protection from light.
As an efficient synthetic building block, the iodine atom of this compound is prone to undergo coupling reactions, thus being widely used in drug chemistry to construct complex molecular frameworks with biological activity. It is particularly of great interest in the development of anti-cancer and antibacterial drugs. At the same time, it is also a key intermediate for the development of probe molecules and functional materials. By further functionalization, its electronic properties and molecular recognition ability can be regulated, and it demonstrates broad application potential in organic optoelectronic materials and biosensing fields.
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C.F |
C8H6IN |
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E.M |
243 |
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M.W |
243 |
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m/z |
243 (100.0%), 244 (8.7%) |
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E.A |
C, 39.53; H, 2.49; I, 52.21; N, 5.76 |
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5-iodoindole, as an organic intermediate with unique chemical structure and properties, has shown broad application prospects in materials science. By conducting in-depth research on the properties and reaction mechanisms of 5-Iodine Indole, as well as developing new synthesis methods and application fields, we can promote the development of 5-Iodine Indole in materials science and provide scientific basis and technical support for its application in more fields.
Synthesis and modification of polymer materials
5-Iodine Indole can be used as a key monomer or intermediate for synthesizing polymer materials. Through polymerization reactions such as free radical polymerization, condensation reactions, etc., 5-Iodine Indolecan be introduced into polymer chains to obtain polymer materials with unique structures and properties.
Modification of polymer materials:
5-Iodine Indole can also be used to modify existing polymer materials. By introducing 55-Iodine Indole groups, the heat resistance, corrosion resistance, mechanical properties, and other properties of polymer materials can be improved. For example, introducing 5-Iodine Indole into polyimide can significantly improve its thermal stability and mechanical properties.
Development And Preparation Of Functional Materials
5-Iodine Indole also holds significant importance in the development and preparation of functional materials. Through specific chemical reactions and structural design, 5-Iodine Indole can be converted into functional materials with specific functions.
Optoelectronic Materials:
The aromatic structure and iodine atoms of 5-Iodine Indole give it unique optoelectronic properties. By introducing 5-Iodine Indole groups, materials with excellent optoelectronic properties can be synthesized, such as organic light-emitting diode (OLED) materials, organic solar cell materials, etc. These materials have broad application prospects in display technology, lighting technology, energy conversion, and other fields.
Simulator:
5-Iodine Indole can also be used to synthesize biomedical materials. By introducing 5-Iodine Indole groups, the biocompatibility and antibacterial properties of biomedical materials can be improved. For example, introducing 5-Iodine Indole into polymers can prepare medical dressings and surgical sutures with antibacterial properties.
Surface Modification And Modification Of Materials
5-iodoindol can also be used for surface modification and modification of materials. Through specific chemical reactions and surface treatment techniques, 5-Iodine Indole can be introduced into the surface of materials to improve their surface properties and application performance.
Surface functionalization:
By utilizing the reactivity of 5-Iodine Indole, specific functional groups or functional groups can be introduced onto the surface of the material. These functional groups or functional groups can endow the material surface with specific properties, such as hydrophilicity, hydrophobicity, anti pollution, etc. This is of great significance for improving the surface properties and application effects of materials.
Surface coating and modification:
5-Iodine Indole can also be used to prepare surface coatings and modification materials. Through specific coating and modification techniques, a layer of coating with specific functions can be formed on the surface of the material. These coatings can protect the material surface from corrosion, wear, and other damages, while endowing the material surface with specific properties such as lubricity, conductivity, etc.
Specific application cases of 5-Iodine Indole in materials science
Synthesis of Polymer Conductive Materials
By introducing 5-Iodine Indole into polymer chains, conductive polymer materials can be synthesized. These materials have broad application prospects in fields such as electronic devices and sensors. For example, by copolymerizing 5-Iodine Indole with polyacetylene, a polyacetylene-5-Iodine Indole copolymer with excellent conductivity can be obtained. This copolymer has important application value in the preparation of electronic devices.
5-iodoindole, as an important organic intermediate, has shown extensive application potential in multiple fields. Especially in the field of spices, its unique chemical structure and properties make it a key raw material for synthesizing various spices.
Basic applications in the field of spices
(1) As a raw material for synthetic fragrances
The iodine atoms and aromatic ring structure in its molecule endow it with unique reactivity. In spice synthesis, it can be used as a starting material to generate spice molecules with specific aromas and properties through a series of chemical reactions such as substitution, addition, coupling, etc. These spice molecules have wide application value in industries such as food, beverage, and cosmetics.
(2) Aroma regulation and enhancement
It may have certain aroma characteristics on its own, but more importantly, it can regulate and enhance the overall layering and complexity of the aroma through interactions with other spice molecules. In spice formulas, it can be used as an auxiliary ingredient to help improve the overall quality and durability of the aroma.
Specific application examples in spice synthesis
(1) Synthesize spices with fruity aroma
Fruit flavored spices have a wide range of applications in the food and beverage industry. Through chemical reactions, spice molecules with specific fruity aromas can be synthesized. For example, by condensation reactions with certain aldehydes or ketones, spices with fruity aromas such as apple and pear can be produced. These spices can significantly enhance the taste and aroma in products such as fruit juice, fruit flavored drinks, and candies.
(2) Synthesize fragrances with floral fragrance
Floral perfume also plays an important role in cosmetics, perfume and other industries. Flavor molecules with specific floral aromas can be generated by reacting with certain alcohol or ester compounds. For example, through its esterification reaction with benzyl alcohol, fragrances with rose or jasmine fragrance can be synthesized. These spices can give unique fragrance and charm to products such as perfume and skin care products.
(3) Synthesize spices with woody aroma
Wooden perfumes are common in men's perfume, household fragrance and other fields. Aromatic molecules with woody aroma can be generated by reacting with certain phenolic or aldehyde compounds. These spices usually have stable and long-lasting aroma characteristics, which can create a warm and comfortable atmosphere.
(4) Synthesize exotic spices
In addition to the common aroma types mentioned above, it can also be used to synthesize exotic spices. For example, by reacting 5-iodoindol with certain compounds containing exotic functional groups, spice molecules with unique aromas and flavors can be generated. These spices have a wide range of application value in the fields of seasonings, specialty foods, and more.
Deep application in spice synthesis
1. Fine aroma regulation
In the advanced perfume and fine fragrance products, the fine control ability has been fully demonstrated. Due to its unique chemical structure, it can interact subtly with various spice molecules, thereby precisely regulating the level, intensity, and persistence of aroma. This ability makes it an important ingredient in the formula of advanced perfume, bringing consumers more delicate and rich fragrance experience.
2. Synthesis of complex aroma combinations
In complex aroma combinations, it can serve as a bridge connecting different aroma molecules, cleverly blending multiple aroma elements together. Through clever chemical reaction design, it can be coupled or condensed with other spice molecules to generate complex compounds with unique aroma characteristics. These compounds play a crucial role in the fragrance process, endowing products with unique aroma personality and charm.
3. Aroma stabilization treatment
Its introduction can also improve the stability of spices. In some cases, spice molecules may be easily degraded or spoiled by factors such as light, heat, or oxygen. The specific chemical structure of 5-iodoindole endows it with certain antioxidant and anti degradation abilities, which can protect other spice molecules from external environmental damage. Therefore, adding an appropriate amount of this product to the spice formula can extend the shelf life and service life of the spice.
Application examples in specific spice types
1. Synthesis of citrus spices
Citrus spices such as lemon and orange have fresh and lively aroma characteristics. By reacting with certain aldehydes or ketones, fragrance molecules with citrus aroma can be synthesized. These spices can bring a pleasant aroma experience in products such as fruit juice drinks and candies.
2. Synthesis of Oriental Fragrance
Oriental spices usually have rich and mysterious aroma characteristics, such as vanilla, cinnamon, cloves, etc. It can react with these spice molecules to generate complex compounds with oriental aroma characteristics. These compounds can create a unique oriental style and atmosphere in perfume, home fragrance and other products.
3. Synthesis of exotic spices
Exotic spices usually have unique and charming aroma characteristics, such as coconut fragrance, mango fragrance, etc. By reacting with compounds containing exotic functional groups, exotic spice molecules can be synthesized. These spices have a wide range of application value in specialty foods, seasonings, and other fields, and can bring consumers a new taste and smell experience.
5-Iodoindole is a versatile building block in organic chemistry, enabling the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Its iodine atom facilitates regioselective functionalization, cross-coupling reactions, and photochemical transformations. As industries prioritize sustainability and precision, innovations in green chemistry (e.g., flow reactors, photocatalysis) will expand its applications. Future research should explore its role in bioconjugation, organic electronics, and AI-driven synthesis, solidifying its position as a cornerstone of modern synthetic chemistry.
Frequently Asked Questions
Why does its melting point fluctuate in the catalogs of different suppliers?
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Purity, crystal habits, and measurement methods together create the melting point "Rashomon".
There are subtle differences in the data from various suppliers: Sigma Aldrich reports 101-104 ° C, TCI reports 97.0-101.0 ° C, and Fisher Scientific reports 95-99 ° C. The lesser known truth is that, in addition to purity factors (97% vs 95%), the crystal morphology, particle size, and heating rate of the capillary melting point analyzer of the sample can all cause a several degree drift in the apparent melting point - it is not a fixed point, but a "mass fingerprint".
How long can the prepared DMSO stock solution survive in the refrigerator?
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-Live for 1 month at 20 ° C and 6 months at -80 ° C, and repeated freezing and thawing are strictly prohibited.
The supplier clearly specifies the storage period for the solution: -20 ° C storage, which must be used up within one month; If placed in a -80 ° C ultra-low temperature refrigerator, it can be extended to 6 months. Cold mechanism: Molecular motion intensifies in solution state, and the ice crystal stress generated by repeated freezing and thawing may damage its structure.
Apart from conventional organic synthesis, what is its "hidden identity" in materials science?
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Can serve as candidate molecules for nonlinear optical (NLO) materials.
A systematic density functional theory (DFT) study in 2021 revealed that 5-iodoindole has significant nonlinear optical properties, and its theoretical calculation parameters indicate its potential application value in this field. This is another 'scientist persona' outside of its role as a drug intermediate.
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