Decapeptide Injection is a type of injectable drug or cosmetic preparation containing active ingredients of decapeptide. Its core component, decapeptide, is a short chain peptide composed of ten amino acids connected by peptide bonds. Different peptides have significant differences in biological activity and clinical applications due to differences in amino acid sequences. Common decapeptides include decapeptide-4, decapeptide-12, etc. These peptides participate in physiological processes such as skin repair and fat metabolism by mimicking the functions of growth regulators or growth factors. For example, decapeptide-4 can promote the production of collagen and elastin, improving skin elasticity; Decapeptide-12 reduces melanin synthesis by inhibiting tyrosinase activity and has whitening effects. It participates in skin growth, healing, and repair processes by simulating growth regulators and growth factors. Localized use can promote the proliferation of keratinocytes and fibroblasts, significantly increasing cell numbers within 72 hours. Its mechanism of action includes: promoting the synthesis of collagen and elastin, enhancing skin elasticity; Support the generation of new skin cells, reduce and prevent fine lines and wrinkles; As a synthetic metabolic peptide in adipose tissue injection, it prevents the production of new triglycerides and reorganizes subcutaneous adipose tissue.
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Decapeptide. COA
Decapeptide Injection is a type of injection formulation primarily composed of decapeptides, which are short chain peptides formed by connecting ten amino acids through peptide bonds. Different types of peptides have different uses in fields such as medical beauty and skin care due to their amino acid sequences and biological activities. Here is its detailed description:
Promoting collagen and elastin production: Decapeptide-4 is a synthetic peptide that mimics growth regulators and growth factors, participating in normal skin growth, healing, and wound repair. Topical use or injection of decapeptide-4 can promote the production of collagen and elastin, improve skin elasticity and firmness. Collagen and elastin are important components for maintaining skin structure and elasticity. As age increases, their synthesis gradually decreases, leading to problems such as sagging and wrinkles in the skin. The injection formulation of decapeptide-4 can improve skin condition at the cellular level by supplementing these key components, making the skin more firm and elastic.Supporting the generation of new skin cells: Decapeptide-4 supports the active generation of new skin cells, reducing and preventing fine lines and wrinkles. It can promote the proliferation of keratinocytes and fibroblasts within 72 hours. Keratinocytes are the main cells in the epidermal layer of the skin, while fibroblasts are the main cells that synthesize collagen and elastin. By promoting the proliferation of these cells, decapeptide-4 can accelerate the process of skin renewal and repair, reducing fine lines and wrinkles caused by skin aging.
Reorganization of adipose tissue
Preventing the production of new triglycerides: Decapeptide-4 can also be used as a synthetic metabolic peptide in adipose tissue injection formulations, which prevents the production of new triglycerides and reorganizes subcutaneous adipose tissue. In some cases, uneven distribution of subcutaneous fat can lead to local fat accumulation or depression in the body, affecting the appearance of the body. The injection formulation of decapeptide-4 can regulate fat metabolism, reduce local fat accumulation, and promote fat redistribution, making body lines smoother. Applied to body shaping: In the field of beauty, decapeptide-4 injection formulations are often used for body shaping, such as improving fat distribution in the abdomen, thighs, buttocks, and other areas. Through precise injection techniques, decapeptide-4 can be injected into the target adipose tissue to achieve local shaping effects.
Decapeptide-12 is a synthetic peptide with the sequence Tyr Arg Ser Arg Lys Tyr Ser Ser Trp Tyr. As a tyrosinase inhibitor, it is responsible for the production of melanin in the skin. Tyrosinase is the core enzyme responsible for melanin production, and its excessive activity can lead to pigmentation (such as pigmentation and uneven skin tone). Decapeptide-12 specifically inhibits tyrosinase activity in the skin, blocking key steps in melanin synthesis and reducing melanin production. Research has shown that at the same dose, the effect of decapeptide-12 in regulating melanin is 5.5 times that of hydroquinone. Decapeptide-12 injection formulation can be used to lighten pigmentation, targeting pigmentation issues such as melasma, freckles, age spots, and sun spots.
Whitening and freckle removal
It can effectively reduce melanin accumulation and brighten skin tone. At the same time, it can also improve uneven skin tone caused by UV damage or aging, making the skin more translucent. Compared with traditional whitening ingredients such as hydroquinone, decapeptide-12 is non irritating, allergenic, or toxic, making it suitable for long-term use on sensitive skin. It is effective even in very small amounts and starts working at concentrations as low as 0.01%. Preliminary clinical research results have shown that the peptide has a significant effect on improving the appearance of melasma. The study participants included those who had previously been unsuccessful after six months of using hydroquinone, retinol, and steroid regimens, but they reported a significant improvement in the effect of decapeptide-12 within just 8 weeks, with a 50% improvement after 16 weeks.
Decapeptide injection is a type of injectable drug or cosmetic preparation that uses decapeptide as the main active ingredient. Decapeptide is a short chain peptide composed of ten amino acids connected by peptide bonds. Different types of decapeptides have different uses in medical beauty, skin care, and other fields due to differences in their amino acid sequences and biological activities：
1.Thymosin injection preparation
Ingredients: Thymosin alpha 1 and other small molecule peptides.
Appearance: Colorless or slightly yellow clear liquid.
Immune regulation: Used as an adjuvant therapy for the treatment of various primary or secondary T-cell deficiency diseases, certain autoimmune diseases, various cellular immune dysfunction diseases, and tumors. For example, various types of severe hepatitis, chronic active hepatitis, chronic persistent hepatitis, and liver diseases such as cirrhosis; Herpes zoster, genital herpes, condyloma acuminatum and other viral infectious diseases; Respiratory diseases such as bronchitis, bronchial asthma, and tuberculosis; Autoimmune diseases such as lupus erythematosus, rheumatic and rheumatoid diseases, ankylosing spondylitis, Guillain Barr é syndrome, etc; Hematological disorders such as aplastic anemia, leukemia, and thrombocytopenia; Viral keratitis, viral conjunctivitis, allergic rhinitis and other facial diseases; Endocrine disorders such as age-related premature aging and menopausal syndrome in women; Multiple boils and facial acne, as well as dermatological diseases such as psoriasis, lichen planus, squamous cell carcinoma, and keratosis; Pediatric diseases such as congenital immunodeficiency in children.
Usage and dosage:
Subcutaneous or intramuscular injection: 10-20mg once a day or as directed by a doctor.
Intravenous drip: 20-80mg once, dissolved in 500ml 0.9% sodium chloride injection or 5% glucose injection, once a day or as directed by a doctor.
Attention: For allergic patients, an intradermal sensitivity test (prepared with a solution of 25 μ g/ml and injected with 0.1ml intradermally) should be performed before injection or after treatment termination. Positive reactions are prohibited. If this product shows abnormal changes such as turbidity or flocculent precipitation, it is prohibited from use.
Storage: Sealed, stored in a cool and dark place.
2.Tixipatide injection preparation
Ingredients: Tilapitide (Tilapitide).
Specifications: There are 6 specifications available for 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, and 15mg each.
Usage: Mainly used for weight loss control, etc. (specific indications need to be determined according to clinical research and drug instructions).
Usage and dosage:
- Initial dose: The recommended initial dose is 2.5mg subcutaneous injection once a week. The dose of 2.5 milligrams is the start of treatment, not for weight loss.
- Dose adjustment: After 4 weeks, increase the dose to 5mg subcutaneous injection once a week. If additional weight loss control is required, increase the dose by 2.5 milligrams at least 4 weeks after the current dose. The maximum dose of ticagrelor is 15mg subcutaneously injected once a week.
- Omission treatment: If a dose is missed, patients should be instructed to use ticacetamide as soon as possible within 4 days (96 hours) after the missed dose. If more than 4 days have passed, the missed dose should be skipped and the next dose should be given on a regularly scheduled day. In each case, patients can resume their regular weekly dosing schedule.
- Change of administration date: If necessary, the date of weekly administration can be changed as long as the interval between two administrations is at least 3 days (72 hours).
Injection method:
- Preparation before injection: Before starting, provide training on correct injection techniques to patients and nursing staff. Guide patients using single dose bottles to use syringes suitable for dosage administration (e.g. a 1mL syringe can measure a dose of 0.5mL).
- Selection of injection site: Subcutaneous injection of tigeriptide in the abdomen, thigh, or upper arm. Every injection requires rotating the injection site.
- Injection time: Inject ticagrelor once a week, at any time of the day, with or without meals.
- Injection procedure: Before use, visually inspect ticagrelor, which should be transparent, colorless to slightly yellow. Do not use ticagrelor if particles or discoloration are visible. When using ticagrelor and insulin, inject them separately and do not mix them. It is acceptable to inject ticagreptin and insulin into the same body part, but the injections should not be adjacent to each other. The specific steps are as follows: there is a piece of disinfectant cotton in the box. After tearing open the packaging, take out the disinfectant cotton inside and wipe the skin of the intended injection site; You can pinch the belly skin with your fingers to make it bulge, making it easier to inject; Take out the needle, remove the cover, with the needle tip facing upwards, gently push the piston until a small amount of liquid flows out from the needle tip; Insert the needle tip into the skin, gently push the piston until the medication is completely injected, complete.
Taboo: Do not use during pregnancy.
3.Other Ten Peptide Injection Preparations
Specific uses of different peptides: Other injectable formulations of peptides may have different uses depending on the type of peptide. For example, certain peptides may have specific cosmetic effects, such as promoting collagen synthesis, improving skin elasticity, reducing wrinkles, etc; Or it may have other medical effects, such as regulating endocrine function, promoting tissue repair, etc. The specific use needs to be determined based on the type of peptide, amino acid sequence, and clinical research results.
Usage and precautions: The usage and precautions of different decapeptide injection formulations may vary. Generally speaking, it is necessary to follow the doctor's advice and use according to the prescribed dosage, frequency, and injection method. At the same time, attention should be paid to disinfection of injection sites, storage conditions of drugs, and monitoring of allergic reactions. Before use, carefully read the drug instructions to understand the indications, dosage, adverse reactions, and other information of the drug.
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