Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of neomycin sulphate injection in China. Welcome to wholesale bulk high quality neomycin sulphate injection for sale here from our factory. Good service and reasonable price are available.
Neomycin sulphate injection belongs to the aminoglycoside antibiotic family. Its molecular structure contains multiple amino rings and glycosidic bonds, which give it unique antibacterial activity. The drug is a white or off-white crystalline powder, easily soluble in water, and stable in nature. It is often used in the form of injection in the medical field with various specifications, the most common of which are 1ml:50mg (50,000 units), 2ml:100mg (100,000 units), etc. The drug exerts its antibacterial effect by inhibiting bacterial protein synthesis and has strong efficacy against Gram-negative bacteria and some Gram-positive bacteria. It has no bacterial activity and is an aminoglycoside antibiotic that is widely used in the clinical treatment of various infectious diseases caused by sensitive bacteria. However, due to the presence of significant nephrotoxicity and ototoxicity, clinical application must strictly follow the indications and dosage specifications.
Additional information of chemical compound:
| Product Name | Neomycin Sulphate Powder | Neomycin Sulphate Tablets | Neomycin Sulphate Injection | Neomycin Sulphate Ointment |
| Product Type | Powder | Tablet | Injection | Cream |
| Product Purity | ≥99% | ≥99% | ≥99% | ≥99% |
| Product Specifications | Customizable | Customizable | Customizable | Customizable |
| Product Package | Customizable | Customizable | Customizable | Customizable |
Our Product
Neomycin Sulphate +. COA
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Certificate of Analysis |
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Compound name |
Neomycin Sulphate | |
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CAS No. |
1405-10-3 | |
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Grade |
Pharmaceutical grade | |
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Quantity |
Customized | |
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Packaging standard |
Customized | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
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Lot No. |
20250109001 |
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MFG |
Jan 12th 2025 |
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EXP |
Jan 8th 2029 |
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Structure |
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| TEST STANDARD | GB/T24768-2009 Industry. Stnndard | |
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Item |
Enterprise standard |
Analysis result |
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Appearance |
White or almost white powder |
Conformed |
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Water content |
≤4.5% |
0.30% |
| Loss on drying |
≤1.0% |
0.15% |
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Heavy Metals |
Pb≤0.5ppm |
N.D. |
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As≤0.5ppm |
N.D. | |
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Hg≤0.5ppm |
N.D. | |
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Cd≤0.5ppm |
N.D. | |
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Purity (HPLC) |
≥99.0% |
99.5% |
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Single impurity |
<0.8% |
0.48% |
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Residue on ignition |
<0.20% |
0.064% |
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Total microbial count |
≤750cfu/g |
80 |
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E. Coli |
≤2MPN/g |
N.D. |
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Salmonella |
N.D. | N.D. |
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Ethanol (by GC) |
≤5000ppm |
400ppm |
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Storage |
Store in a sealed, dark and dry place at-20 degrees |
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Neomycin sulphate injection is a broad-spectrum antibiotic that can effectively kill many different types of bacteria. It can be used to treat a variety of animal diseases, such as reproductive system infections (mycoplasma yellow infection, gonorrhea, etc.), respiratory system infections, conjunctivitis, etc. It can also treat gastrointestinal infections caused by Gram-negative bacteria, and is effective for livestock and poultry intestinal infections, fish diseases, shrimp, crab, shellfish diseases, sea cucumber diseases, etc.
It is mainly used to treat bacterial infections such as respiratory tract, digestive tract, urogenital tract, etc. in pigs, chickens, cattle, sheep and other animals. For example, porcine reproductive and respiratory syndrome, chicken pneumonia, bovine viral diarrhea, swine streptococcal disease, etc. It has a good therapeutic effect on reproductive system infections of animals, such as mycoplasma yellow infection and gonorrhea. In addition, it can also treat respiratory system infections and conjunctivitis in cattle, pigs and other animals.
Neomyci sulfate solution is an aminoglycoside antibiotic for veterinary use, used for gastrointestinal infections caused by Gram-negative bacteria. Neomyci has a strong bactericidal effect on Gram-negative bacteria. It is rarely absorbed when taken orally, and most of it is excreted in the feces in its original form. When the intestinal mucosa is inflamed or ulcerated, absorption can be increased.
Neomyci sulfate has a good effect in treating bacterial intestinal infections in livestock and poultry, and can be used to treat intestinal bacillary diseases such as white dysentery and neomyci typhoid. Neomyci is almost not absorbed in the intestine, and mainly works in the intestine, and its antibacterial efficacy is two to three times that of erythromycin and neobactin.
In terms of the antibacterial spectrum, veterinary neomyci sulfate mainly has a strong effect on Gram-negative bacteria, especially Escherichia coli and Salmonella; large doses of neomyci sulfate also have a good effect on chicken Mycoplasma. However, increasing the dosage of the drug will significantly reduce the economic value of the drug, and it will also increase the probability of adverse reactions.
Neomyci sulfate veterinary drug products are often used for bacterial enteritis and respiratory diseases, and are a commonly used drug. The key issue is that it must be used in combination with other drugs, and at least two or more drugs must be used in combination when prescribing. In the treatment of enteritis-type Escherichia coli, neomyci is used in combination with macrocyclic drugs such as erythromycin thiocyanate, tylosin tartrate or tilmicosin solution.
Veterinary neomyci sulfate can also be used to treat pet eye diseases. Through local use, it can effectively reduce eye inflammation and infection symptoms. At the same time, the drug not only has the efficacy of antibiotics, but also has good anti-inflammatory and immunomodulatory effects. When animals suffer from inflammatory diseases, it can quickly reduce inflammatory symptoms, and at the same time, by regulating the immune system, it helps pets better resist diseases. In the treatment of animal digestive system diseases, veterinary neomyci sulfate can quickly enter the animal body through oral administration and other methods, inhibit the growth of pathogens, reduce symptoms such as diarrhea and vomiting in animals, and help animals restore normal digestive function.
1. Prevent infectious diseases of livestock and poultry, such as yellow diarrhea in piglets, Escherichia coli disease in chickens, and serositis in ducks, reduce livestock and poultry mortality, and improve breeding benefits.
Veterinary neomyci sulfate plays an important role in preventing infectious diseases of livestock and poultry in animal husbandry. For example, for piglet yellow scour, neomyci sulfate can timely control the development of the disease and reduce the risk of death of piglets. In chicken farming, for Escherichia coli disease, it can effectively inhibit the reproduction of pathogens and reduce the incidence rate. For duck serositis, the use of neomyci can significantly improve the overall health level of the duck flock, thereby improving the breeding efficiency.
2. Promote growth and development, enhance the disease resistance of livestock and poultry, improve feed utilization, and shorten the market cycle.
By adding an appropriate amount of neomyci sulfate to the feed, the disease resistance of livestock and poultry can be enhanced.
It helps livestock and poultry to better absorb nutrients, improve feed utilization, and enable livestock and poultry to grow and develop faster, thereby shortening the market cycle. This not only reduces the cost of breeding, but also provides high-quality livestock and poultry products to the market faster.
3. As a vaccine adjuvant, improve the effect of the vaccine.
When neomyci sulfate is used as a vaccine adjuvant, neomycin sulphate injection can enhance the stimulating effect of the vaccine on the animal body and improve the protective power of the vaccine. When mixed with the vaccine, it can make the animal produce a stronger immune response after vaccination and better prevent the occurrence of various diseases.
Precautions for use
When using veterinary neomyci sulfate, you should strictly follow the veterinarian's advice to determine the appropriate dosage and course of treatment. If used in excess, it may cause residual drugs in the animal's body, which not only affects the health of the animal, but also may pose a potential risk to food safety. At the same time, excessive use of drugs can easily lead to drug resistance, making subsequent treatment more difficult.
When using neomyci sulfate, pay attention to the combination with other antibiotics. For example, it reacts to cephalosporin anti-infective drugs in terms of physical and chemical effects and needs to be used separately. It can be used in combination with macrolide antibiotics to treat mastitis caused by Gram-positive bacteria; it has a synergistic effect when used in combination with penicillins or cephalosporins; but it cannot be used in combination with chloramphenicol, and drugs of the same type cannot be used in combination to avoid enhancing toxicity. At the same time, be careful to avoid using it at the same time with drugs that affect the absorption of digitalis drugs, vitamin A or vitamin B12, so as not to affect the efficacy of these drugs.
During the use of neomyci sulfate, pay close attention to the physiological condition of animals. If animals have symptoms such as loss of appetite, nausea, diarrhea, etc., it may be an adverse reaction to the drug. In addition, pay attention to the mental state and excretion of animals. If abnormalities are found, communicate with veterinarians in time to adjust the treatment plan. If animals have symptoms such as a significant decrease in urine volume or urination frequency, thirst, dizziness or unsteady gait, they should also pay attention and take corresponding measures in time.
Drug interactions
The interactions between neomycin sulphate injection and other drugs mainly include:
Increased nephrotoxicity:
Combined with vancomycin, amphotericin B, cyclosporine and other drugs, it can increase the risk of renal tubular damage.
Combined with diuretics (such as furosemide), it aggravates nephrotoxicity by reducing renal blood flow.
Increased ototoxicity:
Combined with other aminoglycosides, cisplatin, ethacrynic acid and other drugs, it can damage the balance of inner ear lymph fluid and cause hearing loss.
Neuromuscular blockade:
Combined with muscle relaxants (such as succinylcholine), ammonium chloride, magnesium sulfate and other drugs, it can enhance neuromuscular blocking effects and lead to respiratory depression.
Affect absorption:
Combined with antacids containing aluminum and magnesium, it can reduce the absorption of neomyci sulfate and reduce the efficacy.
Clinical Research Progress
In recent years, the clinical application research of neomyci sulfate has mainly focused on the following aspects:
Treatment of drug-resistant bacteria:
For multidrug-resistant Gram-negative bacterial infections, the combination of neomyci sulfate and other antibiotics (such as β-lactams) is being explored, and preliminary results show that synergy can improve efficacy.
Topical administration:
Topical preparations of neomyci sulfate (such as eye drops and ointments) have good application effects in ophthalmic and dermatological infections, with a low incidence of adverse reactions.
Pharmacokinetic optimization:
By adjusting the dosage and interval, the blood drug concentration curve is optimized to reduce the risk of toxicity. For example, a once-daily dosing regimen is used to reduce the incidence of nephrotoxicity while ensuring efficacy.
Summary and Outlook
As a classic aminoglycoside antibiotic, neomyci sulfate injection plays an important role in intestinal infections, preoperative preparations and adjuvant treatment of hepatic encephalopathy. However, its ototoxicity and nephrotoxicity limit the scope of clinical application. Future research should focus on the following directions:
Develop new drug delivery systems:
such as targeted preparations and sustained-release preparations to increase the concentration of drugs at the site of infection and reduce systemic exposure.
Treatment strategies for drug-resistant bacteria:
Explore the combination of neomycin sulphate injection and other antibiotics to address the challenge of multi-drug resistant bacterial infection.
Toxicity monitoring technology:
Use biomarkers (such as urine NAGase and blood cystatin C) to detect renal toxicity early and guide dose adjustment.
Through rational use of drugs and continuous research, neomyci sulfate injection is expected to provide more options for clinical infection treatment while ensuring safety.
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