Thiamine nitrate, Also known as vitamin B1 nitrate, its CAS number is 532-43-4, molecular formula is C12H17N5O4S, molecular weight is 327.36, and its appearance is white to slightly yellow crystalline or crystalline powder, with a slight or slightly specific odor. Slightly soluble or slightly soluble in water (solubility varies depending on the source and preparation conditions, such as 1g dissolved in 35mL of water or 1g dissolved in 1mL of 20 ℃ water), slightly soluble in ethanol, methanol or chloroform, insoluble in ether, benzene and acetone. It is stable in air and more stable in neutral solutions than acidic solutions (such as pH=4.0), but is prone to decomposition under neutral and alkaline conditions. Both redox reactions can cause it to lose its activity.
It has the reaction characteristics of nitrate and can undergo specific chemical reactions with certain reagents for its identification. It is used as a source of vitamin B1 for nutritional enhancement in foods such as rice, flour, pastries, soy sauce, etc. In the field of medicine, it is also used as a supplement for vitamin B1. It has excellent anti-static, dispersing, and emulsifying abilities, and is used as a conditioning agent in the field of personal care products, such as adjusting the pH value and viscosity of products. It is irritating to the skin and eyes, although slightly toxic, it usually does not pose a threat to health within the normal range of use. However, excessive intake may lead to adverse reactions.
Additional information of chemical compound:
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Chemical Formula |
C12H17N5O4S |
|
Exact Mass |
327.10 |
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Molecular Weight |
327.36 |
|
m/z |
327.10(100.0%),328.10(13.0%),329.10(4.5%),328.10(1.8%) |
|
Elemental Analysis |
C, 44.03; H, 5.23; N, 21.39; O, 19.55; S, 9.79 |
|
Melting point |
374-392℃ |
|
Density |
1.58 g/cm3 |
|
Storage conditions |
2-8℃ |
|
|
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Thiamine nitrate, also known as vitamin B1 nitrate, is an important chemical substance with a wide range of uses. The following is a detailed explanation of its purpose:
It serves as a source of vitamin B1 and is used as a nutritional supplement in the food industry to enhance the nutritional value of food. Adding this substance to staple foods such as rice and flour can increase the content of vitamin B1 in food and meet the daily needs of the human body for vitamin B1. Pastries and cookies often lose some of their nutritional components during the production process, and adding their substances can compensate for this loss and make the food healthier. Soy sauce and other seasonings are an indispensable part of people's daily diet, and adding them can increase their nutritional value.
Infants and young children are in a critical period of growth and development, with a high demand for vitamin B1. Adding it to infant and toddler food can help meet their growth and development needs. For special populations such as athletes, pregnant women, and breastfeeding women, their demand for vitamin B1 is relatively high. Adding it to the food of these populations can meet their special nutritional needs.
This product enjoys extensive application value in the pharmaceutical industry, serving as a core raw material for clinical intervention and adjuvant therapy targeting vitamin B1 deficiency and various concomitant complications.
Beriberi stands as the most typical clinical disorder triggered by insufficient vitamin B1 intake, which is commonly accompanied by obvious clinical symptoms including lower limb edema, persistent physical soreness and abnormal sensory perception in local body parts. As a high-purity and efficient vitamin B1 supplement source, this product can effectively replenish the lacking nutrient in the human body, thereby achieving definite therapeutic effects on beriberi and alleviating related physical discomforts fundamentally.In addition, long-term vitamin B1 deficiency is highly likely to induce multiple types of peripheral neurological lesions.
It can effectively accelerate gastrointestinal peristalsis and boost the secretion of active digestive enzymes in the body, so as to remarkably relieve and improve various discomforts caused by indigestion. It can also be applied as a reliable auxiliary therapeutic agent for clinical symptoms including neuritis, myocarditis and digestive disorders. This ingredient helps facilitate the repair and physiological regeneration of nervous tissues, optimize human myocardial physiological function and comprehensively strengthen gastrointestinal digestive capacity. Furthermore, it can be used as core raw material to produce diversified vitamin B1 pharmaceutical preparations, such as oral vitamin B1 tablets and medical vitamin B1 injections. These finished dosage forms are easy for patients to take and use daily, and can further elevate the overall clinical treatment efficiency.
In animal husbandry, it is used as a feed additive to improve the growth performance and health status of livestock and poultry. It can promote the growth and development of livestock and poultry, increase body weight and growth rate. It can increase the appetite and feed intake of livestock and poultry, and increase the intake and utilization of nutrients. It can also improve the reproductive performance of livestock and poultry, including increasing conception rate, litter size, survival rate and other indicators.
It can effectively regulate and optimize the physiological function of the endocrine system in livestock and poultry, facilitate the orderly secretion of various sex hormones in vivo, and further accelerate the healthy development and maturation of reproductive cells, which is conducive to improving the overall reproductive performance of breeding animals. Meanwhile, it can efficiently prevent and improve a variety of adverse symptoms caused by vitamin B1 deficiency among livestock and poultry, including multiple peripheral neuropathy, poor gastrointestinal digestion and other common nutritional deficiency diseases.
This substance boasts outstanding anti-static performance, superior dispersing property and stable emulsifying capacity, thus gaining extensive application prospects in personal care and cosmetic raw material industries. It can be formulated into various skin care products as high-efficiency humectant, natural antioxidant as well as mild soothing and anti-allergy functional ingredient. It is able to remarkably elevate the skin's inherent water-locking capacity and effectively restrain excessive trans-epidermal moisture loss, maintaining long-lasting skin hydration. Meanwhile, it can scavenge excess free radicals inside the skin, inhibit oxidative damage and delay the occurrence of premature skin aging signs.
It can also be used as a conditioning agent, emulsifier, and other ingredients in shampoo and conditioner. It can improve the texture and luster of hair, making it softer and easier to manage;
At the same time, it can also reduce the production of dandruff and improve the health of the scalp. In addition to skincare products, shampoo, and conditioner, it can also be used in other personal care products such as toothpaste, shower gel, etc. It can improve the cleaning ability and user experience of these products.
Apart from the above-mentioned mainstream application fields, Thiamine nitrate also possesses diversified application values and can be widely deployed in various other industrial production sectors. This raw material can serve as a practical pH regulator in industrial production, flexibly adjusting the acidity and alkalinity of different liquid solutions. It is capable of undergoing stable chemical reactions with various acidic and alkaline substances to form corresponding derivative salts, so as to precisely regulate and stabilize the overall pH level of the mixed solution. Moreover, it features favorable interfacial activity and outstanding emulsifying performance.
It can effectively stabilize the internal structure of lotions and creams, efficiently avoid component delamination, formula separation and emulsion breakdown during storage and use. Meanwhile, it greatly enhances the overall formulation stability and prolongs the service life of finished lotion products. Besides, it can be adopted as an essential raw material for the synthesis and preparation of various fine chemical products, and applied to participate in diverse organic chemical reactions. To be specific, it is ideal for synthesizing a series of vitamin B1 derivatives and various sulfur-containing functional compounds. In addition, it can also act as a mild reaction catalyst and reaction accelerator in specific chemical synthesis processes, which helps effectively accelerate the overall reaction progress and further raise the final product synthesis yield.
What Are The Deficiencies Of Vitamin B1
Thiamine nitrate deficiency, also known as beriberi, is a systemic disease caused by a lack of vitamin B1 in the body, mainly affecting the digestive, nervous, and circulatory systems. Its symptoms are diverse, as follows:
Neurological symptoms
Sensory and motor disorders: Vitamin B1 deficiency can lead to a decrease in acetylcholine in nerve conduction, which in turn affects the conduction function of sensory nerve fibers, resulting in sensory abnormalities such as numbness, stabbing pain, burning sensation, etc., commonly found in the extremities. At the same time, there may be symptoms such as decreased muscle strength, muscle soreness, and in severe cases, foot and toe ptosis, as well as a cross threshold gait when walking.
Digestive system symptoms
Vitamin B1 deficiency can interfere with glycogen breakdown and fatty acid oxidation processes, thereby affecting the normal functioning of the gastrointestinal tract. This can lead to damage to the gastrointestinal mucosa and a decrease in digestive enzyme activity, resulting in symptoms such as loss of appetite, bloating, diarrhea, or constipation, and may be accompanied by weight loss.
Other symptoms
Some patients may also experience symptoms such as anorexia, nausea, vomiting, oliguria, and peripheral edema. Severe cases may present with hemorrhagic upper cerebral gray matter syndrome or cerebral beriberi, characterized by nystagmus, forgetfulness, disorientation, ataxia, consciousness disorders, and coma.
What is the sales channel scope of this compound?
Professional biochemical reagent supplier
Many professional biochemical reagent suppliers provide sales services for this substance. These suppliers typically have strict quality control systems and a diverse range of products to meet the needs of different customers. For example, some well-known international biochemical reagent brands such as Cayman Chemical and Sigma, as well as some domestic biochemical reagent companies such as Shanghai Zhen Biotechnology, all offer their sales.
Pharmaceutical and health product companies
Due to its effectiveness in preventing and treating vitamin B1 deficiency, some pharmaceutical and health product companies also include it in their product range for sale. These companies usually have a well-established sales network and after-sales service system, which can provide consumers with a convenient and fast purchasing experience.
E-commerce platform
With the rise of e-commerce platforms, more and more biochemical reagents and health products are being sold through e-commerce platforms. Consumers can search and purchase the substance on major e-commerce platforms.These platforms typically have rich product information and user reviews, which can help consumers make more informed purchasing decisions.
In addition to the sales channels mentioned above, there are also some other possible sales channels, such as direct sales, agents, etc. These channels may vary due to factors such as region, brand, etc.
FAQ
Is this safe?
In conclusion, while thiamine nitrate is generally safe and effective for preventing and treating thiamine deficiency, it can cause side effects in some individuals. These side effects range from mild gastrointestinal discomfort and skin reactions to more severe allergic and neurological symptoms.
Is thiamine mononitrate the same as nitrate?
Thiamine mononitrate is a synthetic stable nitrate salt form of vitamin B1. Thiamine mononitrate is also known as vitamin B1 nitrate and has the molecular formula C12H17N5O4S. The molar mass of this compound is about 327.36 g/mol.
What is the function of thiamine nitrate?
Thiamine nitrate is involved in maintaining healthy eye function, and may help to reduce the risk of certain eye disorders. Overall, Vitamin B1 mononitrate is an important nutrient for good health, and ensuring adequate intake is essential for maintaining good health and preventing deficiency-related problems.
What are the negative effects of thiamine?
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