Thiamine Nitrate CAS 532-43-4

Thiamine nitrate, Also known as vitamin B1 nitrate, its CAS number is 532-43-4, molecular formula is C12H17N5O4S, molecular weight is 327.36, and its appearance is white to slightly yellow crystalline or crystalline powder, with a slight or slightly specific odor. Slightly soluble or slightly soluble in water (solubility varies depending on the source and preparation conditions, such as 1g dissolved in 35mL of water or 1g dissolved in 1mL of 20 ℃ water), slightly soluble in ethanol, methanol or chloroform, insoluble in ether, benzene and acetone. It is stable in air and more stable in neutral solutions than acidic solutions (such as pH=4.0), but is prone to decomposition under neutral and alkaline conditions. Both redox reactions can cause it to lose its activity. It has the reaction characteristics of nitrate and can undergo specific chemical reactions with certain reagents for its identification. It is used as a source of vitamin B1 for nutritional enhancement in foods such as rice, flour, pastries, soy sauce, etc. In the field of medicine, it is also used as a supplement for vitamin B1. It has excellent anti-static, dispersing, and emulsifying abilities, and is used as a conditioning agent in the field of personal care products, such as adjusting the pH value and viscosity of products. It is irritating to the skin and eyes, although slightly toxic, it usually does not pose a threat to health within the normal range of use. However, excessive intake may lead to adverse reactions.

Additional information of chemical compound:

Thiamine nitrate, also known as vitamin B1 nitrate, is an important chemical substance with a wide range of uses. The following is a detailed explanation of its purpose:

Nutritional supplements

 

It serves as a source of vitamin B1 and is used as a nutritional supplement in the food industry to enhance the nutritional value of food. Adding this substance to staple foods such as rice and flour can increase the content of vitamin B1 in food and meet the daily needs of the human body for vitamin B1. Pastries and cookies often lose some of their nutritional components during the production process, and adding their substances can compensate for this loss and make the food healthier. Soy sauce and other seasonings are an indispensable part of people's daily diet, and adding them can increase their nutritional value.

 

Infants and young children are in a critical period of growth and development, with a high demand for vitamin B1. Adding it to infant and toddler food can help meet their growth and development needs. For special populations such as athletes, pregnant women, and breastfeeding women, their demand for vitamin B1 is relatively high. Adding it to the food of these populations can meet their special nutritional needs.

Medical use

 

This substance has also been widely used in the field of medicine, mainly for the treatment of vitamin B1 deficiency and related diseases. Beriberi is a typical manifestation of vitamin B1 deficiency, characterized by lower limb edema, pain, and sensory abnormalities. As a source of vitamin B1, it can effectively treat beriberi. Vitamin B1 deficiency can lead to neuropathy, manifested as symptoms such as limb numbness, pain, and decreased muscle strength. It can be used to treat neuritis and improve patients' symptoms. It can also affect the normal function of the gastrointestinal tract, leading to indigestion.

 

It can promote gastrointestinal peristalsis and secretion of digestive enzymes, improving symptoms of indigestion. It can also be used as an adjuvant therapy for diseases such as neuritis, myocarditis, and indigestion. It can promote the repair and regeneration of the nervous system, improve myocardial function, and enhance digestive function in the gastrointestinal tract. It can also be used as a raw material to prepare various vitamin B1 preparations, such as vitamin B1 tablets, vitamin B1 injections, etc. These preparations can be convenient for patients to take and improve treatment effectiveness.

Feed additives

 

In animal husbandry, it is used as a feed additive to improve the growth performance and health status of livestock and poultry. It can promote the growth and development of livestock and poultry, increase body weight and growth rate. It can increase the appetite and feed intake of livestock and poultry, and increase the intake and utilization of nutrients. It can also improve the reproductive performance of livestock and poultry, including increasing conception rate, litter size, survival rate and other indicators.

 

It can improve the endocrine system of livestock and poultry, promote the secretion of sex hormones and the development of reproductive cells. It can also prevent vitamin B1 deficiency in livestock and poultry, such as multiple neuropathy, indigestion, and other diseases. It can enhance the immunity of livestock and poultry, and strengthen their resistance to diseases.

Personal care and cosmetic applications

 

This substance has excellent anti-static, dispersing, and emulsifying abilities, making it widely used in the fields of personal care and cosmetics. It can be used as a moisturizing agent, antioxidant, soothing and anti allergic agent in skincare products. It can improve the moisturizing ability of the skin and reduce the loss of skin moisture; At the same time, it can also resist oxidation and reduce skin aging; In addition, it can also soothe sensitive skin, alleviate symptoms such as redness, swelling, and itching.

 

It can also be used as a conditioning agent, emulsifier, and other ingredients in shampoo and conditioner. It can improve the texture and luster of hair, making it softer and easier to manage; At the same time, it can also reduce the production of dandruff and improve the health of the scalp. In addition to skincare products, shampoo, and conditioner, it can also be used in other personal care products such as toothpaste, shower gel, etc. It can improve the cleaning ability and user experience of these products.

Other industrial applications

 

In addition to the aforementioned application areas, Thiamine nitrate also has a wide range of applications in other industrial sectors. This substance can be used as a pH regulator to adjust the acidity or alkalinity of a solution. It can react with acids or bases to generate corresponding salts, thereby changing the pH value of the solution. It has excellent emulsifying ability and can be used as an emulsifying stabilizer.

 

It can stabilize lotion and prevent it from layering or cracking; At the same time, it can also improve the stability and durability of lotion. It can also be used to prepare other chemicals or as a raw material for certain chemical reactions. For example, it can be used to prepare derivatives of vitamin B1 or other sulfur-containing compounds; At the same time, it can also serve as a catalyst or promoter for certain chemical reactions, improving reaction rates and yields.

Thiamine nitrate deficiency, also known as beriberi, is a systemic disease caused by a lack of vitamin B1 in the body, mainly affecting the digestive, nervous, and circulatory systems. Its symptoms are diverse, as follows:

Neurological symptoms

 

Sensory and motor disorders: Vitamin B1 deficiency can lead to a decrease in acetylcholine in nerve conduction, which in turn affects the conduction function of sensory nerve fibers, resulting in sensory abnormalities such as numbness, stabbing pain, burning sensation, etc., commonly found in the extremities. At the same time, there may be symptoms such as decreased muscle strength, muscle soreness, and in severe cases, foot and toe ptosis, as well as a cross threshold gait when walking.

Digestive system symptoms

 

Vitamin B1 deficiency can interfere with glycogen breakdown and fatty acid oxidation processes, thereby affecting the normal functioning of the gastrointestinal tract. This can lead to damage to the gastrointestinal mucosa and a decrease in digestive enzyme activity, resulting in symptoms such as loss of appetite, bloating, diarrhea, or constipation, and may be accompanied by weight loss.

Other symptoms

 

Some patients may also experience symptoms such as anorexia, nausea, vomiting, oliguria, and peripheral edema. Severe cases may present with hemorrhagic upper cerebral gray matter syndrome or cerebral beriberi, characterized by nystagmus, forgetfulness, disorientation, ataxia, consciousness disorders, and coma.

1.Professional biochemical reagent supplier
Many professional biochemical reagent suppliers provide sales services for this substance. These suppliers typically have strict quality control systems and a diverse range of products to meet the needs of different customers. For example, some well-known international biochemical reagent brands such as Cayman Chemical and Sigma, as well as some domestic biochemical reagent companies such as Shanghai Zhen Biotechnology, all offer their sales.

2.Pharmaceutical and health product companies
Due to its effectiveness in preventing and treating vitamin B1 deficiency, some pharmaceutical and health product companies also include it in their product range for sale. These companies usually have a well-established sales network and after-sales service system, which can provide consumers with a convenient and fast purchasing experience.

3.E-commerce platform
With the rise of e-commerce platforms, more and more biochemical reagents and health products are being sold through e-commerce platforms. Consumers can search and purchase the substance on major e-commerce platforms such as Tmall, JD.com, Taobao, etc. These platforms typically have rich product information and user reviews, which can help consumers make more informed purchasing decisions.

4.Research institutions and university laboratories
For some research institutions and university laboratories, it is one of the commonly used experimental reagents. These institutions usually purchase through professional reagent suppliers or research reagent procurement platforms to ensure the accuracy and reliability of experiments.

5.Other channels
In addition to the sales channels mentioned above, there are also some other possible sales channels, such as direct sales, agents, etc. These channels may vary due to factors such as region, brand, etc.

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