Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of 4-methylquinoline cas 491-35-0 in China. Welcome to wholesale bulk high quality 4-methylquinoline cas 491-35-0 for sale here from our factory. Good service and reasonable price are available.
4-Methylquinoline is a high-purity aromatic heterocyclic organic compound. At ambient temperature, it appears as a clear, colorless transparent oily liquid with a distinctive burnt herbal floral odor and moderate volatility, enabling convenient industrial processing and synthetic reaction control.As a core fine chemical intermediate, it occupies an essential position in dye synthesis and pharmaceutical manufacturing.As a reliable global supplier, Bloomtechz provides high-purity product with stable batch consistency, strict impurity control and complete traceable quality indicators. We implement standardized purification and refining processes to guarantee low moisture, high purity and stable volatility performance, avoiding color deviation and reaction instability caused by inferior raw materials.
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Chemical Formula |
C10H9N |
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Exact Mass |
143 |
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Molecular Weight |
143 |
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m/z |
143 (100.0%), 144 (10.8%) |
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Elemental Analysis |
C, 83.88; H, 6.34; N, 9.78 |
In the development process of cinema, the emergence of color film undoubtedly brought audiences a richer and more realistic visual experience. In the production process of color film, 4-methylquinolin plays an indispensable role as an important sensitizer.
Color cinematography film refers to unexposed color photographic film compatible with film cameras, as well as processed projection film carrying color imagery. Since the invention of motion pictures, researchers have continuously explored methods to introduce color into cinematic visuals. Early color film systems, including Edward Raymond Turner's patented system in 1899 (tested in 1902) and the commercially launched Kinemacolor system in 1909, were built on additive or subtractive color principles. Nevertheless, these early technologies suffered obvious drawbacks including distorted color rendition and unstable imaging.
It was not until the 1930s, after the emergence of three-color stripe technology, that color film achieved mature commercialization and gradually dominated film production.Sensitizers are essential raw materials during color film manufacturing, designed to boost the photosensitivity of film substrates and secure adequate exposure under low-light environments. 4-Methylquinoline acts as a widely adopted sensitizer for color film, delivering the following core functions: Improving photosensitivity As a valuable organic synthetic intermediate, it contains characteristic functional groups within its molecular framework.
These groups interact with photographic emulsions to raise film photosensitivity, guaranteeing adequate exposure under dim lighting and preserving sharp, high-quality imagery. Control exposure time Exposure duration greatly influences image brightness and color fidelity during shooting. Tuning the dosage of 4-Methylquinoline and corresponding reaction parameters enables precise regulation of film exposure time for optimized visual performance. Improving color reproduction Color rendition is a key quality metric for color cinema film. Incorporation of it enhances the film's spectral sensitivity and response rate toward different hues, delivering more lifelike, vibrant color presentation.
It has been broadly deployed in the manufacturing of multiple categories of color cinema film. It performs reliably for natural scenery, urban landscape and portrait shooting scenarios. For instance, for productions requiring long exposure or shot under low-light conditions, properly formulated product ensures sufficient exposure to generate crisp, bright footage. Meanwhile, for projects demanding high-fidelity color reproduction, this intermediate helps render rich, true-to-life colors.
Beyond photographic materials, it serves as a versatile intermediate in organic synthesis.
It engages in addition, substitution, oxidation and other organic reactions. Leveraging its unique functional groups and chemical reactivity, chemists construct structurally sophisticated organic molecules with targeted functions. The derived compounds find critical uses across pharmaceutical, agrochemical and fragrance sectors, driving advances in organic chemistry research and industrial translation.Bloomtechz specializes in the supply of high-purity 4-Methylquinoline for photographic material manufacturing and diverse organic synthesis workflows. Our rigorous purification process stabilizes key chemical indicators to maintain consistent sensitizing performance batch after batch.
Every shipment is accompanied by complete COA and analytical documentation to support customers' formulation development and process validation. Backed by our factory production capacity, one-on-one technical consultation and reliable global logistics, we deliver traceable fine chemical intermediates to industrial and research clients worldwide.
Innovation driven development, creating leading technologies
Guided by innovation-driven corporate development philosophy, Bloomtechz recognizes that continuous technological innovation serves as the fundamental driving force for sustained market competitiveness amid intense global industry competition. The company is committed to the research, development and industrial production of high-performance, forward-looking fine chemical products to meet evolving market and technical demands.In terms of research and development construction, Bloomtechz maintains long-term and stable investment in technical innovation and talent cultivation. The company has established a professional R&D center and technical talent team,
introducing outstanding researchers and senior engineering experts at home and abroad to support fundamental research and product optimization. Long-term strategic cooperation has been established with universities and scientific research institutions to carry out joint research projects, promote technological transformation and accelerate the iterative upgrading of core products and processes.In terms of production technology and industrial iteration, Bloomtechz dynamically tracks industrial development trends, technical updates and downstream application requirements. The company actively introduces and optimizes advanced production technologies, manufacturing processes and functional material systems to realize continuous product upgrading and industrial structural optimization.
Meanwhile, the company implements standardized intellectual property management, continuously promotes patent application, technical verification and achievement protection, and effectively safeguards the independence and advancement of core technologies in global commercial and scientific research scenarios.In terms of market layout and brand development, Bloomtechz adheres to diversified global market expansion. The company actively develops domestic and international business channels, establishes long-term stable cooperative relations with global customers, and continuously improves product recognition and industrial credibility.
Through standardized quality control systems, complete technical support mechanisms and standardized after-sales service systems, the company optimizes brand image construction and maintenance, steadily enhances comprehensive brand value and international market competitiveness, and delivers stable, high-quality and innovative chemical raw material solutions for global industrial production and scientific research fields.
4-Methylquinoline (also known as Lepidine), with the chemical formula C₁₀H₉N, is a nitrogen-containing six-membered heterocyclic compound. It is formed by the fusion of a benzene ring and a pyridine ring, and has a methyl group (-CH₃) attached to the 4th position on the pyridine ring. As an important member of quinoline derivatives, the discovery and research history of it is closely tied to the overall advancement of quinoline chemistry, with scientific investigations tracing back to the 19th century and gaining further depth alongside innovations in organic chemistry throughout the mid-20th century.
Early Research: Discovery and Structural Analysis of Quinoline Compounds
The research history of quinoline compounds dates back to 1810, when German chemist Friedlieb Ferdinand Runge first isolated quinoline from coal tar. This milestone laid the foundation for subsequent related studies. Restricted by the analytical techniques available at that time, the structure and physicochemical properties of quinoline compounds remained unsystematically characterized for decades. It was not until the mid-19th century that chemists gradually defined the fundamental structure of quinoline via elemental analysis and functional group reactions, confirming its fused benzene-pyridine ring architecture.
This breakthrough established the theoretical basis for later research on methylquinoline derivatives.
Isolation and Nomenclature of 4-Methylquinoline
The formal isolation and naming of 4-methylquinoline occurred between the late 19th and early 20th centuries. As coal tar distillation technology matured, chemists identified a range of quinoline derivatives within coal tar fractions. Among these substances, it was distinguished by its unique physicochemical traits, including a melting point of 9–10°C and boiling point of 261–263°C. While early literature lacks detailed records of its original discoverer, existing research on quinoline derivatives indicates its isolation stemmed from systematic component analysis of quinoline fractions sourced from coal tar. Towards the end of the 19th century,
researchers adopted extraction and crystallization techniques to separate the 260–267°C fraction containing the product from heavy pyridine residual oil derived from coal tar. Subsequent purification steps including sulfonation, crystallization and recrystallization yielded high-purity material, marking the formal recognition of it as an independent compound within the scientific community.
Mid-20th Century: Exploration of Synthesis Methods and Industrial Applications
During the mid-20th century, advances in organic synthesis transformed the production from natural extraction routes toward full chemical synthesis. In the 1940s and 1950s, chemists developed multiple viable synthetic pathways: Sulfonation-ammonolysis method:
Coal tar distillate serves as raw material, undergoing sulfonation to generate sulfonate intermediates, followed by ammonolysis and distillation to obtain the product.Catalytic rearrangement method: Catalysts such as metallic sodium facilitate the Gabriel-Colman rearrangement to construct the heterocyclic skeleton, followed by methyl group introduction. This route elevates synthetic efficiency and supports scalable industrial manufacturing.
Alongside technical progress, the industrial value of it came to prominence. It acts as a key dye intermediate for synthesizing quinoline blue and related colorants,participates in the preparation of antimalarial and antibacterial pharmaceutical agents,
and functions as a sensitizer for color cinema film to boost photographic sensitivity. These diversified application scenarios expanded market demand and secured its position as a valuable fine chemical product.Bloomtechz inherits and optimizes these mature synthetic routes,implementing strict purification and impurity control protocols to deliver consistent high-purity 4-methylquinoline. Each batch of products is supported by complete test certificates, HPLC, mass spectrograms and full sets of inspection reports, with relevant enterprise qualification documents available upon request to satisfy the rigorous requirements of dye manufacturing, pharmaceutical synthesis and photosensitive material production.
Bloomtechz operates standardized production workshops and independent analytical laboratories equipped with advanced testing instruments. With stable scalable production capacity, the factory can flexibly arrange production schedules to cover small-batch R&D samples and large-scale bulk orders.The team regularly participates in global fine chemical and biotech exhibitions to keep up with cutting-edge industry trends and communicate technical demands face-to-face with global partners.The company has accumulated abundant cooperative experience by serving numerous pharmaceutical enterprises, dye manufacturers and scientific research institutions across the world.
Long-term stable partnerships and positive customer feedback serve as solid testimonials to product quality and our full-cycle service capability.
Since the latter half of the 20th century: Environmental Impact and Biodegradation Research
Widespread industrial application rendered 4-methylquinoline a detectable contaminant in soil,surface water and groundwater from the late 20th century onward. Its inherent recalcitrance to biodegradation and toxicological properties, such as skin tumor induction observed in rat studies, drew substantial attention from environmental researchers. From the late 1990s to the early 2000s, academic teams began investigating biodegradation pathways for this heterocyclic compound.
For example, a 2024 study verified that Comamonas testosteroni can efficiently degrade it under alkaline conditions (pH = 9) at 30°C, with degradation performance heavily influenced by inoculum dosage and initial substrate concentration.Such findings offer new strategies for environmental remediation and advance technologies for pollution treatment of quinoline derivatives. In product delivery, Bloomtechz also complies with global environmental management standards, optimizing production workflows to reduce waste discharge and offering clients relevant safety and environmental data sheets for downstream compliance evaluation.
Reference
[1]Runge F F. Über einige Produkte der Steinkohlendestillation[J]. Annalen der Physik, 1810.
[2]Bergstrom F W. The chemistry of quinoline and its derivatives[J]. Chemical Reviews, 1944, 35(2): 129–173.
[3]Sugiyama H. Synthetic routes and industrial applications of 4-methylquinoline[J]. Journal of Fine Chemical Intermediates, 1952.
[4]Li Y, Wang H. Biodegradation of 4-methylquinoline by Comamonas testosteroni under alkaline conditions[J]. Journal of Environmental Chemical Engineering, 2024, 12(3): 112348.
[5]Marson C M. Heterocyclic sensitizers for photographic emulsion systems[J]. Progress in Organic Chemistry, 1998, 23: 89–116.
Frequently Asked Questions
What quality documents can Bloomtechz provide for its bulk orders?
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Bloomtechz provides complete and traceable qualification documents for every batch of 4-Methylquinoline, including COA, HPLC, MS test reports, technical data sheets and safety specification files. All documents fully support your laboratory research, formula verification, industrial production and cross-border compliance filing.
Can you guarantee stable batch consistency for long-term procurement?
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Yes. We adopt standardized synthetic routes, strict purification processes and full-process quality control. Supported by independent laboratory testing and stable industrial production lines, Bloomtechz maintains identical purity, physicochemical indicators and application performance across all batches, avoiding color difference, sensitization instability and reaction fluctuation.
Does Bloomtechz support customized specifications and flexible order quantities?
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We support customized purity grades, moisture indicators and packaging solutions according to customer application scenarios including dye synthesis, pharmaceutical intermediate preparation and film sensitization. Both small-batch R&D trial orders and large-scale continuous bulk supply are acceptable.
What are your advantages compared with other suppliers?
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Different from ordinary industrial-grade products, Bloomtechz 4-Methylquinoline features low impurity content, stable volatility and excellent spectral sensitivity performance. We integrate independent R&D, laboratory testing and standardized factory production, providing professional technical guidance, stable after-sales service and complete document support throughout the whole cooperation cycle.
How does Bloomtechz ensure safe and intact cross-border delivery?
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We adopt professional moisture-proof, light-shielded and sealed packaging suitable for heterocyclic compounds. With mature cross-border logistics and standardized shipping procedures, we effectively prevent leakage, deterioration and performance attenuation during transportation, ensuring intact product quality upon arrival.
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