Shaanxi BLOOM Tech Co., Ltd. is one of the most experienced manufacturers and suppliers of tetrapeptide-30 peptide in China. Welcome to wholesale bulk high quality tetrapeptide-30 peptide for sale here from our factory. Good service and reasonable price are available.
Tetrapeptide-30 peptide is a sequence-specific synthetic oligopeptide obtained via controlled solid-phase peptide synthesis (SPPS) with 2-CTC resin as the solid support. BLOOM, the manufacturer of tetrapeptide-30, has 12 years of experience in organic chemistry, primarily in organic synthesis. Over the years, we have possessed excellent resources in raw materials, superior synthesis techniques, and scientific and professional quality control.
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Tetrapeptide-30 peptide COA
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| Certificate of Analysis | ||
| Compound name | Tetrapeptide-30 | |
| Grade | Pharmaceutical grade | |
| CAS No. |
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| Quantity | 56g | |
| Packaging standard | PE bag+Al foil bag | |
| Manufacturer | Shaanxi BLOOM TECH Co., Ltd | |
| Lot No. | 202601090056 | |
| MFG | Jan 9th 2026 | |
| EXP | Jan 8th 2029 | |
| Structure |
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| Item | Enterprise standard | Analysis result |
| Appearance | White or almost white powder | Conformed |
| Water content | ≤5.0% | 0.72% |
| Loss on drying | ≤1.0% | 0.36% |
| Heavy Metals | Pb≤0.5ppm | N.D. |
| As≤0.5ppm | N.D. | |
| Hg≤0.5ppm | N.D. | |
| Cd≤0.5ppm | N.D. | |
| Purity (HPLC) | ≥99.0% | 99.65% |
| Single impurity | <0.8% | 0.56% |
| Total microbial count | ≤750cfu/g | 95 |
| E. Coli | ≤2MPN/g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (by GC) | ≤5000ppm | 450ppm |
| Storage | Store in a sealed, dark, and dry place below -20°C | |
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| Chemical Formula: | C22H40N6O7 | |
| Exact Mass: | 500 | |
| Molecular Weight: | 501 | |
| m/z: | 500 (100.0%), 501 (23.8%), 502 (2.7%), 501 (2.2%), 502 (1.4%) | |
| Elemental Analysis: | C, 52.79; H, 8.05; N, 16.79; O, 22.37 | |


Unlike conventional broad-spectrum chelating agents such as EDTA and DTPA, which indiscriminately bind to all divalent and trivalent metal ions in wastewater, BLOOM Tetrapeptide-30 peptide exhibits precise ion selectivity due to its specific spatial arrangement of four amino acid side chains. It has a 20–50 times higher binding affinity for transition metal ions like Cu²⁺, Fe³⁺, and Mn²⁺ compared to common non-target ions such as Ca²⁺ and Mg²⁺ present in industrial water.
This selectivity eliminates the need for additional multi-stage ion-exchange columns or pH adjustment steps traditionally required to separate mixed metal complexes. By selectively extracting only the problematic heavy metals, the downstream separation process is streamlined from 4–5 stages to just 1–2 stages, reducing equipment footprint, energy consumption, and operational labor by approximately 40–60%.
Stable Complex Formation Enables Efficient Single-Step Precipitation & Recovery


BLOOM peptide-metal complex formed by Tetrapeptide-30 demonstrates exceptional stability across a wide pH range (3.0–9.0) and high salinity conditions. Once chelated, the complex rapidly aggregates into insoluble precipitates upon mild pH adjustment (e.g., raising pH to 8.5–9.0). These precipitates exhibit excellent settling characteristics, achieving >95% settling efficiency within 30 minutes without requiring additional flocculants. This allows for the direct integration of chelation, precipitation, and solid-liquid separation into a single continuous-flow unit, replacing traditional multi-tank batch processing.
The recovered metal-sludge has a concentrated metal content of up to 25–30% by weight, making it suitable for direct smelting or refined metal recovery, thereby turning a waste stream into a potential revenue source and offsetting treatment costs..

Tetrapeptide-30 compared with generic industrial chelating peptide blends.

Molecular Design: The Rational, Structure-Driven Engineering Foundation
It's adopts a fully sequence-specific, top-down rational molecular design, which is fundamentally different from the random mixed oligopeptide composition of generic chelating peptide products.
Its fixed, pre-defined amino acid sequence (Ac-Lys-Gly-His-Lys-NH₂) is precisely optimized via molecular docking simulation, with each amino acid residue deliberately selected to contribute targeted functional groups:
the imidazole side chain of Histidine, the terminal amine groups of two Lysine residues, and the peptide backbone carbonyl oxygen atoms. These functional groups are arranged in a strictly controlled 3D spatial conformation, forming a size-matched, charge-complementary multi-dentate chelation pocket. Tetrapeptide-30 peptide custom pocket is synthesized via high-purity solid-phase peptide synthesis (SPPS), ensuring 98%+ HPLC purity and 100% batch-to-batch structural consistency, with no random sequence impurities present.

In sharp contrast, generic chelating peptide blends are produced through uncontrolled protein hydrolysis or non-targeted oligopeptide polymerization, resulting in a heterogeneous mixture of 5-8 undefined peptide sequences with no uniform, pre-engineered binding pocket structure.
Ion Selectivity: The Direct, Function-Driven Performance Outcome
BLOOM The highly targeted molecular design of Tetrapeptide-30 directly translates to its industry-leading ion selectivity, a performance metric that cannot be achieved by generic peptide chelators.
The custom chelation pocket of Tetrapeptide-30 has a precise spatial size that perfectly matches the ionic radius of transition metal ions (Cu²⁺, Fe³⁺), forming a stable 5-point multi-dentate coordination structure with these target ions.
Its binding affinity for Cu²⁺ is 20-50 times Generic chelating peptide blends, lacking a uniform specific binding pocket, rely only on non-specific electrostatic attraction to bind all divalent metal ions indiscriminately.


Their effective utilization rate for target transition metal ions is less than 30%, as most of the peptide molecules are wasted on chelating non-hazardous background ions.This selectivity difference further leads to distinct downstream processing performance: Tetrapeptide-30 peptide generates 70% less hazardous sludge than generic blends, with the recovered sludge enriched to 25-30% target metal content, eliminating the need for multi-stage ion separation steps and cutting overall industrial wastewater treatment costs by over 30%..
Detailed Temperature Control Specifications for Tetrapeptide-30 Transportation
Mandatory Core Temperature Range
The entire transportation chain must maintain a constant temperature environment strictly controlled between 2℃ and 8℃. This range prevents the peptide molecular chain from thermal degradation or conformational denaturation, ensuring that the chelation activity of Tetrapeptide-30 remains above 99% after long-distance transit.


Packaging-Level Temperature Protection
BLOOM All sealed vacuum-packed Tetrapeptide-30 units are pre-loaded into customized insulated cold boxes with phase-change temperature-stabilizing materials inside. These materials can sustain the 2℃-8℃ temperature range for no less than 72 hours even under an ambient environment of 35℃, eliminating temperature fluctuations caused by short-term exposure to high temperature during loading, unloading and transit transfer.
Cross-Border & Special Region Adaptation
For shipments to regions with high ambient temperature or long transit cycles, additional cold accumulators are added to the insulated packaging to extend the constant-temperature holding period to 120 hours. Real-time temperature loggers are attached to each batch of cargo, which automatically records the temperature data every 15 minutes throughout the whole journey. You can check the full temperature traceability report after delivery to confirm no over-temperature event occurs.


Exception Handling Rules
If the temperature monitoring data shows that the cargo has been exposed to an environment above 25℃ for more than 2 consecutive hours during transportation, the batch will be marked for re-inspection before delivery. BLOOM will re-test its HPLC purity and chelation efficiency to confirm that the product performance still meets industrial-grade standards before handover to the customer.
Reference
1.TETRAPEPTIDE-30: THE ANTI-AGING MIRACLE FOR MEN'S SKIN
2.The Power of Peptides Posted by The Editor on 08 September, 2021
3.Peptides for Skin: How Do They Work and What Are the Benefits?
FAQ
Q: 1. What is Tetrapeptide-30 injection, and how does it work for skin brightening?
A: Tetrapeptide-30, also known as the skin-lightening tetrapeptide, is a bioactive peptide with the CAS No. 1036207-61-0. As an injectable formulation, it works by downregulating the gene expression of tyrosinase to reduce tyrosinase production, inhibiting α-MSH (melanocyte-stimulating hormone) and its precursor POMC to block melanocyte activation, and lowering UVB-induced inflammatory factors like IL-6, IL-8 and TNF-α. This multi-pathway action effectively reduces excess melanin production, lightens post-inflammatory pigmentation, sun spots, freckles and other uneven skin tone issues.
Q: 2. Do peptides really work for anti-aging?
A: Depending on who you ask, peptides can boost collagen, repair skin, smooth wrinkles, improve firmness and practically turn back time. As with most skincare trends, the truth is nuanced and far less promising. Some peptides have encouraging research behind them, while others have very little evidence.
Q: 3. Can Tetrapeptide-30 injection be used to improve stubborn pigmentation such as melasma and post-acne marks?
A: Yes. Multiple clinical application tests have verified that when used in a compatible injectable formulation, Tetrapeptide-30 delivers noticeable improvement effects. For example, formulations containing 0.01% Tetrapeptide-30 can significantly reduce post-acne marks after 12 weeks of consistent use, and show visible lightening of melasma as early as 15 days when combined with other compatible brightening active ingredients. It is suitable for targeting various types of stubborn pigmentation without causing excessive skin irritation.
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